Protein Alignment Hel25E and F57B9.3

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_498514.2
• Gene: F57B9.3 / 186440
• WormBaseID: WBGene00018997
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 397
• Identity: 122/397 - (30%)
• Similarity: 210/397 - (52%)
• Gaps: 19/397 - (4%)

  Fly    18 TTAVENQEAPKKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLGMDIL 82
            |.:|.:..:..|:  |.|..:..| |.|..||.|:||.|...|||.||.:|...:.....|.|:.
 Worm     7 TISVVDSSSSSKE--GNYDEVVES-FDDMELKEELLRGIYGFGFEKPSAIQKSAVAPCTTGKDVT 68

  Fly    83 CQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFG 147
            .|:::|.|||.:.::..||.::..|.: ..|:::...|.:|.:..::.:...:.:......:.|.
 Worm    69 IQSQAGSGKTVISLIDILQGIDCEDAH-LQVILLAPQRGMAQRAHEQLKSLGRNLNVNATCLGFD 132

  Fly   148 GMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIF 212
            ..| :.|:      ..|:::|||...|:.|.:....:|:   |||||.|:||.: ..:..:.|:|
 Worm   133 TTA-ENDK------ISHVLMGTPKDFLSNIPSDTSRIKM---FVLDEADEMLSK-GFKDQIYEVF 186

  Fly   213 RSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLKENE-KNKKLF 276
            ||.|...||::.|||:..::..|..:||:||:.:.|..: :|||.|::|.|:|::::| |...|.
 Worm   187 RSMPQDVQVVLLSATMPSEVLDVTNRFMRDPIRILVKKD-ELTLEGIRQFYINVQKDEWKFNCLC 250

  Fly   277 ELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVAT 341
            :||......|.:||..:.:|...|::.|..........|..|...||.:..:.|.....|:||.|
 Worm   251 DLLKTSRETQALIFCNTRRRVTQLTEQLMSIPIKVSCFHGNMEHNEREDMVKDFNSRNTRVLVTT 315

  Fly   342 NLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFDV 406
            :|..|||:| |.:::.|||:..:.:.|:.|..|.|.||:|||.|:|.: |||...|.::::.:..
 Worm   316 DLMARGMNI-RKSLIINYDVSGNMENYMLRNGRQGNFGSKGLPISFFT-ENDISDLKKIENHYST 378

  Fly   407 NISELPE 413
            .|.|:||
 Worm   379 RIEEMPE 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	61/207 (29%)
		SF2_C_DEAD	259..388	CDD:350174	42/129 (33%)
F57B9.3	NP_498514.2	DEAD-like_helicase_N	19..391	CDD:475120	119/385 (31%)