Protein Alignment Hel25E and hel-1

DIOPT Version :9

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001021985.1
• Gene: hel-1 / 174333
• WormBaseID: WBGene00001840
• Length: 425
• Species: Caenorhabditis elegans
• Alignment Length: 425
• Identity: 331/425 - (77%)
• Similarity: 367/425 - (86%)
• Gaps: 6/425 - (1%)

  Fly     3 DNDDLLDYEDEE---QTETTAVENQEAPKKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHP 64
            :.:.|||||:|:   |.:...|...:|.|  .||||.||||||||||||||||||||.|||||||
 Worm     2 EEEQLLDYEEEQEEIQDKQPEVGGGDARK--TKGTYASIHSSGFRDFLLKPEILRAIGDCGFEHP 64

  Fly    65 SEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKE 129
            |||||||||||:||||::||||||||||||||:.|||||||.|... .|:.||||||||||||||
 Worm    65 SEVQHECIPQAILGMDVVCQAKSGMGKTAVFVITTLQQLEPVDGEV-SVVCMCHTRELAFQISKE 128

  Fly   130 YERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDE 194
            |||||||:|.||||||||||||:||||.|.:..||||||||||:|||.|:.||.|..:|:|||||
 Worm   129 YERFSKYLPGVKVAVFFGGMAIKKDEERLANDCPHIVVGTPGRMLALARSGKLKLDKVKYFVLDE 193

  Fly   195 CDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGL 259
            ||||:...|||||||||.:.||..||||||||||.|::|.|||:|||||||||||||||||||||
 Worm   194 CDKMIGDADMRRDVQEIVKMTPQQKQVMMFSATLPKELRTVCKRFMQDPMEVYVDDEAKLTLHGL 258

  Fly   260 QQHYVNLKENEKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERL 324
            |||||.|||.|||::|..|||.|||||||||||:|:||.||.|||||||||:|.|||.|.|||||
 Worm   259 QQHYVKLKEAEKNRRLLNLLDALEFNQVVIFVKAVKRCEALHQLLTEQNFPSIAIHRQMAQEERL 323

  Fly   325 NRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVS 389
            :|||.||||||||||||:||||||||||||||||||||||||:||||||||||||||||||||||
 Worm   324 SRYQAFKDFQKRILVATDLFGRGMDIERVNIVFNYDMPEDSDSYLHRVARAGRFGTKGLAITFVS 388

  Fly   390 DENDAKILNEVQDRFDVNISELPEEIDLSTYIEGR 424
            ||||||.||.||||||::|:||||:||:|||||||
 Worm   389 DENDAKTLNSVQDRFDISITELPEKIDVSTYIEGR 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	162/207 (78%)
		SF2_C_DEAD	259..388	CDD:350174	109/128 (85%)
hel-1	NP_001021985.1	PTZ00424	43..414	CDD:185609	302/371 (81%)
		DEADc	43..245	CDD:238167	157/202 (78%)
		HELICc	260..386	CDD:238034	106/125 (85%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166619
Domainoid	1	1.000	250	1.000	Domainoid score	I1154
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	655	1.000	Inparanoid score	I414
Isobase	1	0.950	-	0	Normalized mean entropy	S103
OMA	1	1.010	-	-		QHG54017
OrthoDB	1	1.010	-	-		D274153at33208
OrthoFinder	1	1.000	-	-		FOG0001601
OrthoInspector	1	1.000	-	-		oto17334
orthoMCL	1	0.900	-	-		OOG6_101150
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1410
SonicParanoid	1	1.000	-	-		X1003
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.890