Protein Alignment CG14015 and Manea

DIOPT Version :10

• Sequence 1: NP_608937.1
• Gene: CG14015 / 33780
• FlyBaseID: FBgn0031716
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_542963.2
• Gene: Manea / 140808
• RGDID: 620327
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 140/509 - (27%)
• Similarity: 224/509 - (44%)
• Gaps: 95/509 - (18%)

  Fly     8 KTRRKLKILLLLAIVALLVITIIVLGSSGRNAAIELLLDERFIARAYRPGDQPQVAEKPPPVAVA 72
            |.||:..|:|.|.||   .|..:::|       :::|              .|..|...||..:.
  Rat     3 KFRRRTCIILSLFIV---FIFSLMMG-------LKML--------------WPNAASFGPPFGLD 43

  Fly    73 LLQPQRENGVIVPEKYDEQKIKERIIQSKIDLMKQQQQRD--------H--EAEQSSRTTLDVVI 127
            ||...|.....:..|.|.|:      ..:||:  :...:|        |  .|.:.:...|..:.
  Rat    44 LLPELRPPNTHLENKADFQR------SDRIDM--ETNTKDLKGAGVTVHPPRASEVNLEELPPLN 100

  Fly   128 SAVHIFYTAPVPWYKSKKPPP----------PPAEH-----PNDVPLTTPRPVRILNTAFYPALG 177
            ..||.||.:   ||.:   |.          |..||     ..:.|.....|...:.::|||.||
  Rat   101 YFVHAFYYS---WYGN---PQFDGKYVHWNHPVLEHWDPRIAKNYPQGRHSPPDDIGSSFYPELG 159

  Fly   178 LYKP-SGSLLAQHFENIRSCGIGVLILSF----SGGKPAEAA--LLHQILELAPQHNLSVTFELS 235
            .|.. ..|::..|.:.:||..||||.||:    :..:..||.  |:..||:.|.::||.|||.:.
  Rat   160 SYSSRDPSVIETHMKQMRSASIGVLALSWYPPDASDENGEATDYLVPTILDKAHKYNLKVTFHIE 224

  Fly   236 VAGNQSVEFVRQQLQEIA-TYTSLAGFYKVWSQSRGVSLPVLYVSNAYKLSDSLGRLLCRSP--- 296
            ...|:..:.:.|.::.|. .|.:...||: :....|.|||:.|:.::|          ...|
  Rat   225 PYSNRDDQNMHQNVKYIIDKYGNHPAFYR-YKTRMGHSLPMFYIYDSY----------ITKPKTW 278

  Fly   297 -SLVEPDGLRRI----LDALFIGHIRLKSHADVLRRLCFDGFYSKLPSNGAVFASTWKNWSYLKS 356
             :|:.|.|.:.:    .|.|||..:..:.|...:.:..|||.|:...:||..:.|:.:||:.|||
  Rat   279 ANLLTPSGSQSVRGSPYDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWNKLKS 343

  Fly   357 FALSYKMLFVPTVGPGFAERNKFPRHGDIQRHRSNGRYYGVAWRTAILNHVGFINIASYNNWPDG 421
            |.....|:|:|:||||:.:.:..|.:....|:|.||:||.|....|:......|:|.|:|.|.:|
  Rat   344 FCEKNNMIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEVGLSAALQTQPSLISITSFNEWHEG 408

  Fly   422 SQIEEVMPR----AGFLDYNPGSRTKYLDLTAHWVGNFLKTRQEAAAAAS-PAS 470
            :|||:.:|:    ..:|||.|...:.||::|..|...:.|.|...|.... |||
  Rat   409 TQIEKAVPKRTANTVYLDYRPHKPSLYLEITRKWSEKYSKERMTYALDQQLPAS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14015	NP_608937.1	GH99_GH71_like	130..453	CDD:470237	107/357 (30%)
Manea	NP_542963.2	Catalytic. /evidence=ECO:0000305	60..462		119/426 (28%)
		Glyco_hydro_99	98..448	CDD:435273	107/366 (29%)