DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq6 and coq6

DIOPT Version :9

Sequence 1:	NP_608934.1	Gene:	Coq6 / 33777	FlyBaseID:	FBgn0031713	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001006829.1	Gene:	coq6 / 448564	XenbaseID:	XB-GENE-945926	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	480	Identity:	206/480 - (42%)
Similarity:	272/480 - (56%)	Gaps:	43/480 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LASAGQARLLSVRLLASKSTTDMTTNRGESTQSTSTEHFDIIIGGGGLVGTTLAAALAKNSTLAD 75
            |..:..:|||  |:|:.        ::|.:..||....:|::|.|||:|||.:|.||..:..|..
Frog     4 LGGSSLSRLL--RMLSQ--------SQGRALSSTGPAVYDVVISGGGMVGTAMACALGSDPHLQH 58

  Fly    76 KKVLLLEGA--------PEFRGFNPTGPYQNRVSAINHNSIELFKSIDAWKHIESARYKPVKQMQ 132
            |||||||..        ||        .:.||||:|...|..|..|..||.||.:.|.||.|:||
Frog    59 KKVLLLEAGNRKPFDHLPE--------NFSNRVSSITPGSATLLASFGAWDHILAMRLKPYKRMQ 115

  Fly   133 VWESNTDALIQFQHDNFASDVACIIENDLILDAVYALAKE----SPNVEILNKARIQCVRLPRDS 193
            ||::.:||||.|..|.. .|:..|:|||:|::   ||.|:    |.:||::.::|......|...
Frog   116 VWDACSDALITFDKDAL-EDMGYIVENDIIIE---ALTKQLELMSDHVEVMYRSRALSYSWPPPY 176

  Fly   194 NSNHS----ELQLEDGRNFSCDLLIGADGANSVVRKEMNVDVFSLNYDRMGLVATLELGEDACDN 254
            |:..:    |::|.||:.....|||||||.||:||....:.....||:...:||||.|.| |.||
Frog   177 NNGKATPWVEIELADGQRLHTKLLIGADGHNSMVRSAAGMQSVQWNYNHAAVVATLHLSE-ATDN 240

  Fly   255 SVAWQRFLPNGPVALLPLTDRLSSLVWSTTNEQAKMLQALPPTEFVDALNEAFCRQYPRVELADK 319
            :||||||||.||:|||||:|..|||||||:.|.|..|.::....|||.:|.||.......|....
Frog   241 NVAWQRFLPTGPIALLPLSDTCSSLVWSTSPEHASELVSMDEESFVDTVNSAFWSNENHSEFITS 305

  Fly   320 AVQALN---SLFGHNGSQHQVQYPPRVCGVLDKSRATFPLGFLHASSYVCNGAALVGDAAHRVHP 381
            |...|:   |.|...||..: |.||.|..|...|||:||||..||:.|:.:..||:|||||||||
Frog   306 AGSLLHSALSFFMPTGSSPR-QLPPSVSRVEQNSRASFPLGLKHATEYIRHRVALIGDAAHRVHP 369

  Fly   382 LAGQGVNLGFSDVRYLVESLAAGAYAGFKLGDKQHLIKYERKCLAKNVPIMLGVHGLHTLYATQF 446
            |||||||:||.||..|...|:..|:.|..||..:||::||.:....|:|:|..|..|..||.|:.
Frog   370 LAGQGVNMGFGDVACLAHHLSQAAFNGSDLGSTKHLLEYETERQRHNLPLMAAVDLLKRLYNTKQ 434

  Fly   447 SPVVLLRSLGLQLTQNLPPVKNLFM 471
            .|:||||:||||.|..|.|||...|
Frog   435 PPIVLLRTLGLQATNALTPVKEQIM 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq6	NP_608934.1	Ubi-OHases	58..476	CDD:273913	192/433 (44%)
Coq6	NP_608934.1	COQ6	58..471	CDD:273914	191/431 (44%)
coq6	NP_001006829.1	NADB_Rossmann	32..459	CDD:419666	196/440 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6039
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2371
OMA	1	1.010	-	-		QHG54916
OrthoDB	1	1.010	-	-		D418762at33208
OrthoFinder	1	1.000	-	-		FOG0003239
OrthoInspector	1	1.000	-	-		otm48496
Panther	1	1.100	-	-	LDO	PTHR43876
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R236
SonicParanoid	1	1.000	-	-		X1881
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110