DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq6 and Coq6

DIOPT Version :9

Sequence 1:	NP_608934.1	Gene:	Coq6 / 33777	FlyBaseID:	FBgn0031713	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001011983.1	Gene:	Coq6 / 299195	RGDID:	1311149	Length:	476	Species:	Rattus norvegicus

Alignment Length:	478	Identity:	197/478 - (41%)
Similarity:	261/478 - (54%)	Gaps:	38/478 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ARLLSVRLLASKSTTDMTTNRG------ESTQSTSTEHFDIIIGGGGLVGTTLAAALAKNSTLAD 75
            |.||.||..   ||..:....|      ..|.|::...:|:::.|||:||:.:|.||..:....|
  Rat     9 AGLLCVRWW---STAQLAARGGPLVACRRWTSSSTDSVYDVVVSGGGMVGSAMACALGHDIHFHD 70

  Fly    76 KKVLLLEGAPEFRGFNPTGPYQNRVSAINHNSIELFKSIDAWKHIESARYKPVKQMQVWESNTDA 140
            ||:||||..|:......:..|.||||:|:..|..|..|..||.||.:.|.|..::||||:|.::|
  Rat    71 KKILLLEAGPKKTLEKLSETYSNRVSSISLGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEA 135

  Fly   141 LIQFQHDNFASDVACIIENDLILDAV-YALAKESPNVEILNKARIQCVRLP-----RDSNSNHSE 199
            ||.|..||. .|:..|:|||:|:.|: ..|...:..|::|.:::......|     .|| |....
  Rat   136 LIMFDKDNL-DDMGYIVENDVIMHAITKQLEAVADRVKVLYESKAVGYAWPGPFSLADS-SPWVH 198

  Fly   200 LQLEDGRNFSCDLLIGADGANSVVRKEMNVDVFSLNYDRMGLVATLELGEDACDNSVAWQRFLPN 264
            :.|.||......|||||||.||.||:...:.....|||:..:||||.|.| |.:|:||||||||:
  Rat   199 ITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVGWNYDQSAVVATLHLSE-ATENNVAWQRFLPS 262

  Fly   265 GPVALLPLTDRLSSLVWSTTNEQAKMLQALPPTEFVDALNEAFCRQYPRVELADKAVQALNSLFG 329
            ||:|||||:|.||||||||::..|..|.::...|||||:|.||.......:..|.|     |...
  Rat   263 GPIALLPLSDTLSSLVWSTSHAHAAELVSMHEEEFVDAINSAFWSDVHHTDFVDSA-----SAMV 322

  Fly   330 HNGSQHQV-----------QYPPRVCGVLDKSRATFPLGFLHASSYVCNGAALVGDAAHRVHPLA 383
            |    |.|           |.||.|..|..||||.||||..||:.||....||:|||||||||||
  Rat   323 H----HAVALLKPTKVSARQLPPSVAKVDAKSRALFPLGLGHAAEYVRPRVALIGDAAHRVHPLA 383

  Fly   384 GQGVNLGFSDVRYLVESLAAGAYAGFKLGDKQHLIKYERKCLAKNVPIMLGVHGLHTLYATQFSP 448
            |||||:||.|:..|:..|:..|:.|..||...||..||......|..::.....|..||:|..:|
  Rat   384 GQGVNMGFGDISSLIHYLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSTTP 448

  Fly   449 VVLLRSLGLQLTQNLPPVKNLFM 471
            :||||:.|||.|..:.|:|...|
  Rat   449 LVLLRTWGLQATNAVSPLKEQIM 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq6	NP_608934.1	Ubi-OHases	58..476	CDD:273913	183/431 (42%)
Coq6	NP_608934.1	COQ6	58..471	CDD:273914	182/429 (42%)
Coq6	NP_001011983.1	Ubi-OHases	57..475	CDD:273913	180/424 (42%)
Coq6	NP_001011983.1	NADB_Rossmann	57..471	CDD:304358	180/424 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347740
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0654
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6039
Inparanoid	1	1.050	308	1.000	Inparanoid score	I2543
OMA	1	1.010	-	-		QHG54916
OrthoDB	1	1.010	-	-		D418762at33208
OrthoFinder	1	1.000	-	-		FOG0003239
OrthoInspector	1	1.000	-	-		oto97041
orthoMCL	1	0.900	-	-		OOG6_102655
Panther	1	1.100	-	-	LDO	PTHR43876
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1881
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770