| Sequence 1: | NP_608934.1 | Gene: | Coq6 / 33777 | FlyBaseID: | FBgn0031713 | Length: | 477 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_033296.1 | Gene: | Sqle / 20775 | MGIID: | 109296 | Length: | 572 | Species: | Mus musculus |
| Alignment Length: | 494 | Identity: | 106/494 - (21%) |
|---|---|---|---|
| Similarity: | 176/494 - (35%) | Gaps: | 148/494 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 34 TTNRGESTQSTSTEHF---DIIIGGGGLVGTTLAAALAKNSTLADKKVLLLE---GAPE------ 86
Fly 87 -----FRGFNPTGPYQNRVSAINHNSIELFKSIDAWKHIESARYKPVKQMQV----WESN-TDAL 141
Fly 142 IQFQHDNFASDVACIIENDLILDAVYALAKESPNVEILNKARIQCVRLPRDS---NSNHSELQLE 203
Fly 204 DGRNFSCDLLIGADGANSVVRKEMNVDVFSLNYDRMGLVATLELGEDACDNSVAWQRFLPNGPVA 268
Fly 269 LLPLTDRLSSLVWSTTNEQAKMLQALPPTEFVDALNEAFCRQ-YPRV--ELADKAVQALNSLFGH 330
Fly 331 NGSQHQVQYPPRVCGVLDKSRATFPLGFLHASSYVCNGAALVGDAAHRVHPLAGQGVNLGFSDVR 395
Fly 396 ----------------------------------YLVESLAAGAYAGFK-LGDKQHLI------- 418
Fly 419 -KYERKCLAKNVPIM--LGVHGL----H----TLYATQF 446 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Coq6 | NP_608934.1 | Ubi-OHases | 58..476 | CDD:273913 | 95/467 (20%) |
| COQ6 | 58..471 | CDD:273914 | 95/467 (20%) | ||
| Sqle | NP_033296.1 | Interaction with MARCHF6. /evidence=ECO:0000250|UniProtKB:Q14534 | 1..98 | ||
| Required for degradation in response to high membrane cholesterol levels. /evidence=ECO:0000250|UniProtKB:Q14534 | 61..72 | ||||
| Sufficient for enzyme activity. /evidence=ECO:0000250|UniProtKB:Q14534 | 116..572 | 100/482 (21%) | |||
| UbiH | 123..497 | CDD:223727 | 89/439 (20%) | ||
| NADB_Rossmann | 124..>174 | CDD:304358 | 14/53 (26%) | ||
| NADB_Rossmann | 275..546 | CDD:304358 | 64/294 (22%) | ||
| Hydrophobic, mediates interaction with membranes. /evidence=ECO:0000250|UniProtKB:Q14534 | 514..572 | 6/18 (33%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0654 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||