DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6907 and ELP4

DIOPT Version :9

Sequence 1:	NP_001285628.1	Gene:	CG6907 / 33775	FlyBaseID:	FBgn0031711	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_015224.1	Gene:	ELP4 / 856002	SGDID:	S000006022	Length:	456	Species:	Saccharomyces cerevisiae

Alignment Length:	484	Identity:	103/484 - (21%)
Similarity:	165/484 - (34%)	Gaps:	162/484 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GTRTSPHTAQVITSSGNPYLDVVIGG-GLPMGSICLIEEDRFMTHAKVLAKYFLAEG-------- 70
            |.|.||.|:|..||:|:..||.::|. |||:|:..|:||........:|.|.|.|:|
Yeast    74 GVRPSPATSQPTTSTGSADLDSILGHMGLPLGNSVLVEEQSTTEFHSILGKLFAAQGIVHNRISD 138

  Fly    71 --------------VISKQEIFLGSLDDIPAEMLRRLPRPLTDQESMEQSEVQALGDA-----GA 116
                          |:|..::|...|..|.....:::.:.|..:|..:.: ||.|.:.     ..
Yeast   139 SSADKTRNGDTHVIVLSLNQMFAKELPGIYKGSRKQMKKNLISEEESKVT-VQNLNETQRSTPSR 202

  Fly   117 ENGLRIAWRYNDLPLVNSEHATAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVIDEEFSK 181
            ...|:|||:|.                                              :.||:  :
Yeast   203 YKDLKIAWKYK----------------------------------------------LADEK--R 219

  Fly   182 SSSPTTPSLEQQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTGSQDSP 246
            ..||....::|                             |:...:.|:...:|:........|.
Yeast   220 LGSPDRDDIQQ-----------------------------NSEYKDYNHQFDITTRLMPAPIASE 255

  Fly   247 LQVFHNPR--YKGLLNDIQQLL-RNESFVAGTKNNLCRVCLTSLGSPLWYDE------------H 296
            | .|..|.  ...:|:.|:|.: ||:       ..|.|:.:.||..|..|..            |
Yeast   256 L-TFIAPTQPVSTILSQIEQTIKRND-------KKLIRIVIPSLLHPAMYPPKMFESSEIIGLMH 312

  Fly   297 FGEDLIKFL---TLLMASVRNCNSVCLITMPMHLIAKYDASLVPKIRQLVDYAIELESFAGSERE 358
            ....|:|..   .:|.||:    |:.:||.|:.::          :|.:.|..|.||.|.....|
Yeast   313 GVRSLVKKYYERVVLFASI----SIDIITPPLLVL----------LRNMFDSVINLEPFNQEMTE 363

  Fly   359 -------THPAFKEYSGLLHLHKMSAINTLAVHMPETPDLAFKLRRKKFIIEKFHLPPELQESSA 416
                   :.|. |...||:|:.|:..............:.|||..||||.||::.:|.:..|.||
Yeast   364 FLERVYKSQPG-KIQHGLVHILKLPVFTDRGEMRVLKSEWAFKNGRKKFEIEQWGIPVDDAEGSA 427

  Fly   417 KPDNC--------ISGLLSNSNATASLDF 437
            ..:..        ||..:.......|||:
Yeast   428 ASEQSHSHSHSDEISHNIPAKKTKISLDY 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6907	NP_001285628.1	PAXNEB	3..436	CDD:283315	101/481 (21%)
ELP4	NP_015224.1	PAXNEB	70..456	CDD:398965	102/482 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3949
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55433
OrthoFinder	1	1.000	-	-		FOG0004319
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103712
Panther	1	1.100	-	-	LDO	PTHR12896
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R393
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.830