DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6907 and elp4

DIOPT Version :9

Sequence 1:	NP_001285628.1	Gene:	CG6907 / 33775	FlyBaseID:	FBgn0031711	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	XP_009301242.1	Gene:	elp4 / 550331	ZFINID:	ZDB-GENE-050417-114	Length:	432	Species:	Danio rerio

Alignment Length:	418	Identity:	142/418 - (33%)
Similarity:	207/418 - (49%)	Gaps:	90/418 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TSFRKRTVQKP--IRGTRTSPHTAQVITSSGNPYLDVVIGGGLPMGSICLIEEDRFMTHAKVLAK 64
            |||:|:|..|.  |.|||.|....|::.|||...||.||||||.:|::.|:||||:.:::::|.|
Zfish    18 TSFQKKTRSKLVFIPGTRPSVQNGQLLVSSGVSSLDYVIGGGLAVGTLLLVEEDRYDSYSRMLLK 82

  Fly    65 YFLAEGVISKQEIFLGSLDDIPAEMLRRLPRP-LTDQESMEQSEVQAL-GDAGAENGLRIAWRYN 127
            ||||||::...|:||.|..|.|.::::.||.| |.|..||:.||.|:. .|....:.::|||||.
Zfish    83 YFLAEGIVCGHELFLASARDHPDQIMQELPSPILDDVASMKMSEGQSQPNDPDNPDTMKIAWRYQ 147

  Fly   128 DLPLVNSEHA-TAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVIDEEFSKSSSPTTPSLE 191
            :.|.|.:..| :::.||:::..:.||..:|...|              ....:....:|.|..|.
Zfish   148 NQPRVQTALASSSRFGHYYDASKTMDPELLQAAK--------------YHSFYQLQETPVTTGLS 198

  Fly   192 QQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTGSQDSPLQVFHNPRYK 256
            ..|                                                  ||        |.
Zfish   199 SLP--------------------------------------------------SP--------YL 205

  Fly   257 GLLNDIQQLLRNESFVAGTK----NNLCRVCLTSLGSPLWYDEHFGED-------LIKFLTLLMA 310
            .||..||.|::.|.|...|.    .|:.||.|.||||.||.|:...:|       |..||..|..
Zfish   206 ALLKSIQTLIQKEGFDGSTPQLRGRNVLRVGLHSLGSVLWGDDVCCKDNSAHCHALSTFLYALRG 270

  Fly   311 SVRNCNSVCLITMPMHLIAKYDASLVPKIRQLVDYAIELESFAGSERETHPAFKEYSGLLHLHKM 375
            .:|...||.::|:|.|||  ...:::.:|.:|.|.||.||||.|||:||:|.:|:|.|||::.::
Zfish   271 LLRTSLSVAMMTVPSHLI--QSRAVMGRIIRLSDTAIALESFRGSEKETNPLYKDYHGLLYVRQI 333

  Fly   376 SAINTLAVHMPETPDLAFKLRRKKFIIE 403
            ..:|.|...:|:|.||||||:||:|.||
Zfish   334 PRLNCLTSEVPDTKDLAFKLKRKQFTIE 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6907	NP_001285628.1	PAXNEB	3..436	CDD:283315	141/417 (34%)
elp4	XP_009301242.1	PAXNEB	19..361	CDD:283315	139/415 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595662
Domainoid	1	1.000	239	1.000	Domainoid score	I2233
eggNOG	1	0.900	-	-		E1_KOG3949
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32433
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3279
OMA	1	1.010	-	-		QHG55433
OrthoDB	1	1.010	-	-		D413334at33208
OrthoFinder	1	1.000	-	-		FOG0004319
OrthoInspector	1	1.000	-	-		oto39712
orthoMCL	1	0.900	-	-		OOG6_103712
Panther	1	1.100	-	-	LDO	PTHR12896
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R393
SonicParanoid	1	1.000	-	-		X5407
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800