DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6907 and elp4

DIOPT Version :9

Sequence 1:	NP_001285628.1	Gene:	CG6907 / 33775	FlyBaseID:	FBgn0031711	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_588202.1	Gene:	elp4 / 2538987	PomBaseID:	SPCC11E10.06c	Length:	361	Species:	Schizosaccharomyces pombe

Alignment Length:	471	Identity:	116/471 - (24%)
Similarity:	177/471 - (37%)	Gaps:	147/471 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SFRKRTVQK--PIR---GTRTSPHTAQVITSSGNPYLDVVIGGGLPMGSICLIEEDRFMTHAKVL 62
            ||:::...:  |..   |.|.|...|:.|||||:...|..:.||:||.|:.:||||. |.:|.||
pombe     2 SFKRKAAPQIAPTNLPTGVRLSSKDARWITSSGSSSFDYYLSGGIPMKSLLVIEEDS-MDYASVL 65

  Fly    63 AKYFLAEGVISKQEIFLGSLDDIPAEMLRRLP----RPLTDQESMEQSEVQALGDAGAEN----- 118
            .|:|.|||:.....|:||  ..|.....|:||    ||..::.|           ||.:|
pombe    66 LKFFAAEGLKQDHVIWLG--PSIGEMWFRQLPGDSDRPNKNENS-----------AGEDNHSSPP 117

  Fly   119 -------GLRIAWRYNDLPLVNSEHATAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVID 176
                   .::|||||
pombe   118 SKNPQQERMKIAWRY-------------------------------------------------- 132

  Fly   177 EEFSKSSSPTTPSLEQQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTG 241
            |:.||:.:||   |:..|       ||                  ..::.:.:.:..|.|..|..
pombe   133 EQVSKTKAPT---LDMIP-------PG------------------YTHSFDLSKNLIVKSDMKYA 169

  Fly   242 SQDSPLQVFHNPRYKGLLNDIQQLLRNESFVAGTKNNLCRVCLTSLGSPLWYD------EHFGED 300
            ....||:...|| |..::..:.:.|  .:...||   :||:.|.|:.||.:|.      :||
pombe   170 VSPFPLETGSNP-YAPVIESLTRFL--STLTPGT---VCRLVLPSILSPAFYSIRATHPQHF--- 225

  Fly   301 LIKFLTLLMASVRNCNSV---CLITMPMHLIAKYDASLVPKIRQLVDYAIELESFAGSER----E 358
             |:|:..|.:.::...||   |:.::|..|.:: |...:..:..|......|..|...|.    .
pombe   226 -IRFIHTLSSLIKCTTSVHLICMCSVPSTLFSR-DCEQIFWLENLASAVFSLHPFPVKETVNGLV 288

  Fly   359 THPAFKEYSGLLHLHKMSAINTLAVH--MPETPDLAFKLRRKKFIIEKFHLPPELQESSAKPDNC 421
            |.|.     ||..:||:........|  ..|..||:|.:.:::|.||.:.|||...|   :.|..
pombe   289 TQPL-----GLFRIHKLPLALPFTNHANSNEAGDLSFTVSKRRFTIEPWVLPPLDDE---QKDTK 345

  Fly   422 ISGLLSNSNATASLDF 437
            ||..........||||
pombe   346 ISNTNPQKQPVKSLDF 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6907	NP_001285628.1	PAXNEB	3..436	CDD:283315	113/468 (24%)
elp4	NP_588202.1	PAXNEB	2..360	CDD:283315	113/468 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	78	1.000	Domainoid score	I2390
eggNOG	1	0.900	-	-		E1_KOG3949
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	78	1.000	Inparanoid score	I1872
OMA	1	1.010	-	-		QHG55433
OrthoFinder	1	1.000	-	-		FOG0004319
OrthoInspector	1	1.000	-	-		oto100709
orthoMCL	1	0.900	-	-		OOG6_103712
Panther	1	1.100	-	-	LDO	PTHR12896
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R393
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.860