Protein Alignment Vps52 and Vps52

DIOPT Version :10

• Sequence 1: NP_608931.1
• Gene: Vps52 / 33774
• FlyBaseID: FBgn0031710
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001366339.1
• Gene: Vps52 / 224705
• MGIID: 1330304
• Length: 728
• Species: Mus musculus
• Alignment Length: 665
• Identity: 336/665 - (50%)
• Similarity: 486/665 - (73%)
• Gaps: 16/665 - (2%)

  Fly    13 LDNEEVREILKNTTDLRQYSRQIEKEFKEVENKSIEDYIAESQNIANLHNQINDCDDVLERMENM 77
            |::|.|:|.||...|||.||:|:|.|.:::|.|||.|||.||:|||:|||||..||.||||||.|
Mouse    65 LEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQM 129

  Fly    78 LMSFQSVLNNISTEITQLQRKSVSMSLQLTNRQSVKAQLSQFIEDMAVSEEMINIIMETPVTERD 142
            |.:|||.|::||:||..||.:|.:|:::|.|||:|:.:|.:.::.:.|...::..|:|.||||..
Mouse   130 LGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPR 194

  Fly   143 FSTQLNVLNHKLSLVKELSFKESKSTSDVSDVLQKLRLKAMAKIRSYLLEQIYKFRKPMTNYQIP 207
            |..||..|:.|.:.|:|.....:.:.:||..||.:||:||:.|||.::|::||.|||||||||||
Mouse   195 FLEQLQELDAKAAAVREQEAMGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNYQIP 259

  Fly   208 QNAMLKHKFFFEFILSNERHVAQEICSEYIDTMGKIYYSYFKSYSTRLTSLKFEESCTKDDLMGI 272
            |.|:||::||::|:|.|||..|:||..||::|:.|||.||::||..||..:::||...||||||:
Mouse   260 QAALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYVGRLMKVQYEEVAEKDDLMGV 324

  Fly   273 EDNASKGLFSKTTSLKHKSTIFTIGKRGDILN-QQLEAPIIVPHAQLK--NRYTAEALFRSEQYA 334
            ||.|.||.||| .||:.::||||:|.||.::: .:|||||:|||...:  .||..||||||:.||
Mouse   325 EDTAKKGFFSK-PSLRSRNTIFTLGTRGTVISPAELEAPILVPHTAQRGEQRYPFEALFRSQHYA 388

  Fly   335 LVDNACREYLFVTEFFMVRGTQAQDLFNQIMGKTLTLMIKNLETSIHDCFDTIAMFLCIHLIFRY 399
            |:||:||||||:.|||:|.|..|.|||:.:||:||::.:|:||:.:.||:|.||:|||||::.|:
Mouse   389 LLDNSCREYLFICEFFIVSGPAAHDLFHAVMGRTLSMTLKHLESYLADCYDAIAVFLCIHIVLRF 453

  Fly   400 QLMCHKRCVPALDKYWDSLQAVIWPRFELVFRLNIQSIHDCDPTKF-NKELGPHY-----ITRRY 458
            :.:..||.|||||:||:.:.|::||||||:..:|:||:...||.:. ..:..|||     |||||
Mouse   454 RNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYVRASKITRRY 518

  Fly   459 AEFSAAIVGISEHFPNELVSRLLLELQNEVECFILRMAAIFPTRKDQLIYLINNYDLVLGVLMEH 523
            ||||:|:|.|::..|||...:||.:||.|||.|:||:||.|.:||:||::||||||::||||||.
Mouse   519 AEFSSALVSINQTIPNERTLQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMER 583

  Fly   524 TRDNSKEAEAFREQLNSRSAEYVEEILAPHFGGIIQFVKECEHFFEKEQMDELRKQERRSLALVA 588
            ..|:|||.|:|::.||:|:.|::||:|:|.|||::.||||.|...|:.|.:.||.:|.|...|:.
Mouse   584 AADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIR 648

  Fly   589 SFSANWKKSLEELNREVLLSFPSLLTGSQLLQLALASLVQYYHRFHKLLT-PN-----ARAQLTN 647
            .|.::||.|:|.|:::|:.||.:...|:.::|.||..|:|.|||||::|: |.     |||:|.|
Mouse   649 GFGSSWKASVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELIN 713

  Fly   648 IHVVMVEIKKYKSNY 662
            ||.:|||:||:|.|:
Mouse   714 IHHLMVELKKHKPNF 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps52	NP_608931.1	Vps52	42..546	CDD:282044	267/512 (52%)
Vps52	NP_001366339.1	Vps52	94..606	CDD:282044	271/520 (52%)