Protein Alignment CG14020 and TMEM231

DIOPT Version :10

• Sequence 1: NP_001260097.1
• Gene: CG14020 / 33771
• FlyBaseID: FBgn0031707
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_001070884.2
• Gene: TMEM231 / 79583
• HGNCID: 37234
• Length: 369
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 72/309 - (23%)
• Similarity: 117/309 - (37%)
• Gaps: 45/309 - (14%)

  Fly    19 LCSFASLLVLAFIALSVMLPVLLVSLLSPYSGISESRVLY-EQPNVEFNYEYIFVGTTDQGEYEE 82
            ||..|.....|...|...||..|.:     ||....|..| |||.|.|.::.:.|....    .|
Human    74 LCHEAPRARSARAGLPNRLPTALFN-----SGFWLKRSSYEEQPTVRFQHQVLLVALLG----PE 129

  Fly    83 EESLVACSSFSQFNE-QMESYTNSCTTTRYWTEDVDYDGVTDRAHFQLELQDVPT-RLVSFNLLV 145
            .:..:|.|:|..||. |.:.......:||  .||.:.||.||..||:|||....| .::...|::
Human   130 SDGFLAWSTFPAFNRLQGDRLRVPLVSTR--EEDRNQDGKTDMLHFKLELPLQSTEHVLGVQLIL 192

  Fly   146 FFEAELQHKCDLSPPSVLAHQLQLPLHARLRNGHVQLKGELQLKQYVEFTCPFPGRNIKTQFRQV 210
            .|...|.....|...|:...|...|    :....:.:.|:|:|:|....:|  .|.:.:.....:
Human   193 TFSYRLHRMATLVMQSMAFLQSSFP----VPGSQLYVNGDLRLQQKQPLSC--GGLDARYNISVI 251

  Fly   211 QLDTNSTNGNIDQFKMESLLAQVK----------ANPAYFQLAVQETYYRETSARLQPGLIIDLE 265
                |.|:.....:.:..::|..:          .||.:.       ..|...|......||...
Human   252 ----NGTSPFAYDYDLTHIVAAYQERNVTTVLNDPNPIWL-------VGRAADAPFVINAIIRYP 305

  Fly   266 LDVLQVAARYHLSIWERLGQFWLYFASFFGISFYIMNKLKDFLFGRHIV 314
            ::|:.    |....||.:...|:.:.|...|..::..::|.|:|...:|
Human   306 VEVIS----YQPGFWEMVKFAWVQYVSILLIFLWVFERIKIFVFQNQVV 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14020	NP_001260097.1	TM231	1..318	CDD:462964	72/309 (23%)
TMEM231	NP_001070884.2	TM231	95..348	CDD:462964	64/284 (23%)