Protein Alignment mid and TBX15

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_005271218.1
• Gene: TBX15 / 6913
• HGNCID: 11594
• Length: 635
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 187/531 - (35%)
• Similarity: 261/531 - (49%)
• Gaps: 110/531 - (20%)

  Fly   128 QTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLET 192
            |:..::|::.|..||    ||.   |..|:.:.....|.|...:          .::.:|..|:.
Human    72 QSTGSDSEVLTERTS----CSF---STHTDLASGAAGPVPAAMS----------SMEEIQVELQC 119

  Fly   193 KELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRS 257
            .:||.||||:||||||||.||||||.:||..:|    :.|..:|.:.|||:|:|:|||||.||.|
Human   120 ADLWKRFHDIGTEMIITKAGRRMFPAMRVKITG----LDPHQQYYIAMDIVPVDNKRYRYVYHSS 180

  Fly   258 AWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIH 322
            .|:|||.||...|.|:|.||||..|.:...:||:||:|:||||||:|..|.|:|:|||:||||:|
Human   181 KWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVH 245

  Fly   323 LVRLSHGQSI-PSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLT 386
            ::|......: |:.|..:.| ..||:.|||||||.|||||||.||:||||.||||||||||.|
Human   246 VIRKDFSSDLSPTKPVPVGD-GVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGR-- 307

  Fly   387 DFDRDPMEALLLEQQL-RSPLR--LFPD--PLMQQFA----AQG--------DPSSMALFEKARQ 434
              :|..:||::..... |.|:|  .|.|  .:.:|.|    :||        :..::.|:|:...
Human   308 --NRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQASKKTSQGYTVNQHSSETDAIELYERRVW 370

  Fly   435 HLQMFG--GNSPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQW------PQLTAGFLASA 491
            .::..|  |.||...........|::....|...||   .||:....:      .||....|:..
Human   371 LMERRGSTGTSPTTSSTGTPSPSASSHLLSPSCSPP---TFHLAPNTFNVGCRESQLCNLNLSDY 432

  Fly   492 NQQAAAAQAAAQA----------QAQAQAAAAAMAA-----NRTP------PPPPT--------- 526
            ...|.:..||.|:          :.|:...:|...:     .|||      |.||:
Human   433 PPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEA 497

  Fly   527 -----ASTPSS------------TSSGSP----SPDMRPRQYQRFS---PYQLPGGQGPPS-SAA 566
                 .|.|:|            :||.||    ...|:...|..||   ||.|.|...|.| ..|
Human   498 YGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLA 562

  Fly   567 GSPPAVNASRS 577
            .||..::||:|
Human   563 ASPEKLSASQS 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	113/199 (57%)
TBX15	XP_005271218.1	TBOX	113..308	CDD:238106	114/203 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740