Protein Alignment mid and TBX6

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_004599.2
• Gene: TBX6 / 6911
• HGNCID: 11605
• Length: 436
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 146/427 - (34%)
• Similarity: 197/427 - (46%)
• Gaps: 89/427 - (20%)

  Fly   151 PQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRM 215
            |.:.||         ||...||:.:.|     |..|...||.:|||..|..:||||||||.||||
Human    70 PPAMGT---------EPAPSAPEALHS-----LPGVSLSLENRELWKEFSSVGTEMIITKAGRRM 120

  Fly   216 FPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSP 280
            ||..|||.:|    :.|..||..|:|:||:|..|||:...|  |..:|||:|..|.|:|.|||||
Human   121 FPACRVSVTG----LDPEARYLFLLDVIPVDGARYRWQGRR--WEPSGKAEPRLPDRVYIHPDSP 179

  Fly   281 FSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLS-----HGQSIPSNPKELQ 340
            .:.....:|.:||.:|||||:.:|.:|.::|:|||:|||||||||.:     |...:.|
Human   180 ATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMAS------ 238

  Fly   341 DLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLRSP 405
                  :.||||.|.:||||||..||:|||.:||||||||::.|....:||..    ::::||.
Human   239 ------FRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDAR----VKRKLRG- 292

  Fly   406 LRLFPDPLMQQFAAQGD----PSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPP 466
                |:|...:....||    |....|           ||:...:.   |:...|...|...|.|
Human   293 ----PEPAATEAYGSGDTPGGPCDSTL-----------GGDIRESD---PEQAPAPGEATAAPAP 339

  Fly   467 PPG----------LGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTP 521
            ..|          ..|||......|..:..|..:.:...:|..:||..:....:..:..     |
Human   340 LCGGPSAEAYLLHPAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGY-----P 399

  Fly   522 PPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGG 558
            ..||..........|.|.|          .||..|||
Human   400 AAPPAVPFAPHFLQGGPFP----------LPYTAPGG 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	99/203 (49%)
TBX6	NP_004599.2	TBOX	90..277	CDD:238106	99/204 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..339		19/90 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..379		2/18 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740