Protein Alignment mid and TBX1

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_016884414.1
• Gene: TBX1 / 6899
• HGNCID: 11592
• Length: 545
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 199/620 - (32%)
• Similarity: 254/620 - (40%)
• Gaps: 188/620 - (30%)

  Fly    13 VPAAPAAPNASGQTT-----TTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVD 72
            :|.:||..:.|..|.     |.:|.|:.|:|..|..||....:....||       |.......|
Human    44 LPGSPAGMHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPRE-------PPPPPPRYD 101

  Fly    73 VDVVDCSDAEEPPTKARRLNHHQHHQHHQHHHNNNNNNNNNNVAHKSRNSGGAVAQTASAESQLN 137
            ........|..||....                          |:....:.|| |.:|:||
Human   102 PCAAAAPGAPGPPPPPH--------------------------AYPFAPAAGA-ATSAAAE---- 135

  Fly   138 TSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDL 202
                         |:.||.  |.......||:|..|:.|         |...||.|.|||.|:.|
Human   136 -------------PEGPGA--SCAAAAKAPVKKNAKVAG---------VSVQLEMKALWDEFNQL 176

  Fly   203 GTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADP 267
            |||||:||.|||||||.:|...|    :.|...|.:|||.:|:|.||||||:|.|:|||||||||
Human   177 GTEMIVTKAGRRMFPTFQVKLFG----MDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADP 237

  Fly   268 APPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSI 332
            |.|.|::.|||||.......||::||:|:|||||.:|.||.|:||||||||||.|:|.:...:..
Human   238 ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDS 302

  Fly   333 PSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALL 397
            ....:|    :.||:||.||.|||||||||..||:|||.||||||||||... .|:.|:.....|
Human   303 EKYAEE----NFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP-EDWPRNHRPGAL 362

  Fly   398 LEQQLRSPLRLFPDPLMQQFAAQ----GDPSSMALFEK----ARQHLQMFGGNSPYAQLMMPQMY 454
                          |||..||..    ..|:..:..||    ||:..|...|
Human   363 --------------PLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAG------------- 400

  Fly   455 QAAAAAAGPPPPPPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANR 519
              ..|..|.|..|             |||.|..|:.:                  ...|..|...
Human   401 --GPAVLGDPAHP-------------PQLLARVLSPS------------------LPGAGGAGGL 432

  Fly   520 TPPPPPTASTPSSTSSGSPSPDMR-------------PRQY------------QRFSPYQLPGGQ 559
            .|.|......||     .|:|::|             |.:|            .|.:||.|||.:
Human   433 VPLPGAPGGRPS-----PPNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLR 492

  Fly   560 G--------------PPSSAAGSPPAVNASRSPAH 580
            |              |.|.||.:..|..|:.:.|:
Human   493 GHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAAN 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	114/198 (58%)
TBX1	XP_016884414.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141529
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740