Protein Alignment mid and tbx2

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001030291.1
• Gene: tbx2 / 619588
• XenbaseID: XB-GENE-1018115
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 611
• Identity: 182/611 - (29%)
• Similarity: 248/611 - (40%)
• Gaps: 215/611 - (35%)

  Fly   131 SAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKEL 195
            :||:.|:.|:.....:.:........|..||      |:..||:.              ||.|||
 Frog    60 AAEAGLHVSALGHHHQAAHLRSLKSLEPEEE------VEDDPKVT--------------LEAKEL 104

  Fly   196 WDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWL 260
            ||:||.|||||:|||:||||||..:|..||    :....:|.:||||:..|..||:  :|.|.|:
 Frog   105 WDQFHKLGTEMVITKSGRRMFPPFKVRVSG----LDKKAKYILLMDIVAADDCRYK--FHNSRWM 163

  Fly   261 VAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVR 325
            |||||||..|.|:|.|||||.:.|....:.::|.|:|||||..||:|..:|||||:||||.|:||
 Frog   164 VAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVR 228

  Fly   326 LSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD--------- 381
            .:....:|.:       ..:|||||||.|.|||||||..||:||||:|||||||||
 Frog   229 ANDILKLPYS-------TFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKR 286

  Fly   382 ------SSRLTD----FDRDPMEALLL-------EQQLRSPLRLFPDPLM-------QQFAAQGD 422
                  |.|:.:    .|||..|:...       ...|.|||...|.||.       ::|.|..|
 Frog   287 KQLSLPSLRMYEEQCKADRDGAESDASSCDPAPGRDSLHSPLSTEPSPLRLHRSNREEKFGADSD 351

  Fly   423 ----------------------PSSMALFEKARQ-----------HLQMFGGNSPYA-------- 446
                                  |||..|.::.:.           ..:..||::.::
 Frog   352 QELDRREVRTARSHSPVGHRSPPSSPRLEDRGKDKNTPEKKSESPESRKDGGDNVFSRSLEKDKG 416

  Fly   447 -------------------QLMMPQMYQAAAAAAGPPPPPPGLGAFHM---------FQQQWPQL 483
                               :...|.|.|..:        ||.|.|.|:         .||.:..|
 Frog   417 ESRRKEDSKSDPECGSLSKETFAPLMVQTDS--------PPHLSASHLQSLALSGLHGQQFFNPL 473

  Fly   484 TA-----------------------GFLASANQQAAAAQAAAQAQAQAQAAAAA--------MAA 517
            .|                       |.|.::...|:|....:.:..|....||.        |.|
 Frog   474 NAAQPLFIHPGQFTMGPGAFSAMGMGHLLASMTGASALDNGSLSSVQGATGAATFPFHLSQHMLA 538

  Fly   518 NRTPPPP-----------------PTASTPSSTSSGSPSP------DMRPRQYQRFSPYQLPGGQ 559
            ::..|.|                 ..||...:||:.:..|      ..|||  .||:|||:|
 Frog   539 SQGIPMPAFGGLFPYPYTYMAAAAAAASAMPATSAATTMPRNPFLSSTRPR--LRFNPYQIP--- 598

  Fly   560 GPPSSAAGSPPAVN-------ASRSP 578
                  .|.||:.|       ||.:|
 Frog   599 ------VGIPPSTNLLTTGLSASLNP 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	107/213 (50%)
tbx2	NP_001030291.1	T-box	97..277	CDD:366363	104/206 (50%)
		T-box	99..277		104/190 (55%)
		TBX	295..370	CDD:372213	15/74 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	606..660		4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910