Protein Alignment mid and tbx2a

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_005165613.1
• Gene: tbx2a / 573084
• ZFINID: ZDB-GENE-990917-4
• Length: 690
• Species: Danio rerio
• Alignment Length: 586
• Identity: 173/586 - (29%)
• Similarity: 224/586 - (38%)
• Gaps: 226/586 - (38%)

  Fly   166 EPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQI 230
            |.|:..||:.              ||.|||||:||.:||||:|||:||||||..:|..:|    :
Zfish    87 EDVEDDPKVT--------------LEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVNG----L 133

  Fly   231 QPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEK 295
            ....:|.:||||:..|..||:  :|.|.|:|||||||..|.|:|.|||||.:.|....:.::|.|
Zfish   134 DKKAKYILLMDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHK 196

  Fly   296 VKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAY 360
            :|||||..||:|..:|||||:||||.|:||.:....:|.:       ..:|||||||.|.|||||
Zfish   197 LKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYS-------TFRTYVFPETDFIAVTAY 254

  Fly   361 QNQLITKLKIDSNPFAKGFRD-------------------SSRLTD----FDRD----------- 391
            ||..||:||||:|||||||||                   |.|:.|    .|||
Zfish   255 QNDKITQLKIDNNPFAKGFRDTGNGRREKSLNFRKQLAMPSMRMYDDQCKVDRDGGDSDDSSCEQ 319

  Fly   392 ------------PMEALLL------------------------------EQQLRSPL-------- 406
                        |..:.|.                              ||:.:||.
Zfish   320 TTGRDSVHSPTGPATSPLKFTRSREDKNFNESDNELDQHDDGMIRVSSPEQRPQSPFSPRCEDRV 384

  Fly   407 --RL-------FPD-----------------------------------------------PLMQ 415
              ||       :.|                                               |||.
Zfish   385 KDRLNLEKKGDYSDSRKENDSAFSIRHLDKDKLDARNVKDQDSSKKEADSVGMSTVKDGFSPLMV 449

  Fly   416 Q------FAAQGDPSSMALFEKARQHL---------------QMFGGNSPYAQLMMPQMYQAAAA 459
            |      |:| ....|:||.....||.               |.....|.::.:.|..:..:.:.
Zfish   450 QTENPSHFSA-SHLQSLALSGLHNQHFFNPLSSGQSLLFHPGQFAMTPSAFSTMGMGHLLASMSG 513

  Fly   460 AAG------------PPPPPPGLGAFHMFQQQWPQLT--AGFLASANQQAAAAQAAAQAQAQAQA 510
            |:|            .|.|.|...:.||...|...:.  .|.|.......|||.|||.|.
Zfish   514 ASGLENGSLSSQSTSSPNPFPFHLSQHMLASQGISMPTFGGLLPYPYTYMAAAAAAASAL----- 573

  Fly   511 AAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPPSS--AAGSPPAVN 573
                          |..|..||.|......:.|||  .||||||:|......|.  ..|.|..::
Zfish   574 --------------PAGSAASSLSRNPFLNNTRPR--LRFSPYQIPMSFSQSSGLLTTGIPSTMS 622

  Fly   574 A 574
            |
Zfish   623 A 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	104/214 (49%)
tbx2a	XP_005165613.1	T-box_TBX2_3-like	91..275	CDD:410314	104/210 (50%)
		TBX	297..372	CDD:432659	9/74 (12%)