Protein Alignment mid and TBX22

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001103348.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 174/488 - (35%)
• Similarity: 231/488 - (47%)
• Gaps: 111/488 - (22%)

  Fly   152 QSPGTEDSEERLT-----PEPVQKAPKIVGS------CNCD----------DLKPVQCHLETKEL 195
            :..|.|:.|||.:     .||::|.||...|      |..|          :.|.:|..|:..||
Human    37 EKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSEL 101

  Fly   196 WDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWL 260
            |.||||:||||||||.||||||:|||...|    :.|..:|.|.:|::|:|||||||.||.|.|:
Human   102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKG----LDPGKQYHVAIDVVPVDSKRYRYVYHSSQWM 162

  Fly   261 VAGKAD-----PAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPR 320
            |||..|     |    |.|.|||||.|.|...:|:|||:::||||||||..|.|:|.|||:|:||
Human   163 VAGNTDHLCIIP----RFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPR 223

  Fly   321 IHLVR------LSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGF 379
            :|::.      ||..||:|:.       ..||:.|.||.||.|||||||.||||||:.|||||||
Human   224 VHVIEQGSSVDLSQIQSLPTE-------GVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281

  Fly   380 RDSSRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQFAA---QGDPSSMALFEKARQHLQMFGG 441
            ||:.|    :|..::.||.....|....|.    .:.|.|   .|...|..:....       |.
Human   282 RDTGR----NRGVLDGLLETYPWRPSFTLD----FKTFGADTQSGSSGSSPVTSSG-------GA 331

  Fly   442 NSPYAQLMMP----QMYQAAAAAAGPPPPPPGLGAFHM----------FQQQWPQLTAG--FLAS 490
            .||...|:.|    .|:....::.|.|.|...|...::          |.||.|.:...  .|||
Human   332 PSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLAS 396

  Fly   491 ANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQY-------- 547
            :|...:.|....:.                    |..|:...|:|.|.|.:....||
Human   397 SNSSQSLAPLMMEV--------------------PMLSSLGVTNSKSGSSEDSSDQYLQAPNSTN 441

  Fly   548 QRFSPYQLPGGQGPPSSAAGSPPAVNASRSPAH 580
            |.....|.||....|:|.  :|.|::.|..|::
Human   442 QMLYGLQSPGNIFLPNSI--TPEALSCSFHPSY 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	113/209 (54%)
TBX22	NP_001103348.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91		13/53 (25%)
		TBOX	91..287	CDD:238106	114/214 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740