Protein Alignment mid and tbx6

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001007995.1
• Gene: tbx6 / 493357
• XenbaseID: XB-GENE-6257419
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 481
• Identity: 156/481 - (32%)
• Similarity: 217/481 - (45%)
• Gaps: 115/481 - (23%)

  Fly   143 SQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLK-PVQCHLETKELWDRFHDLGTEM 206
            ||.....||.:|.:      |.|.|.....::...|....|. .|:.:||.||||.:||.:||||
 Frog    58 SQRILGAPPLTPLS------LPPGPALGFGQLQPPCETPQLPGNVKMNLENKELWKQFHSIGTEM 116

  Fly   207 IITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPA 271
            ||||:||||||..:||.:|    ::|..:|.:|.||:|:|:.||::...|  |..:|:|:|..|.
 Frog   117 IITKSGRRMFPQCKVSVTG----LEPDGKYLLLADIVPIDNSRYKWQEDR--WEPSGRAEPRLPE 175

  Fly   272 RLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNP 336
            |:|.|||||.......||.|||.|:|||||.:|:.|.|:|:|||:||||.|:||
 Frog   176 RVYIHPDSPAPGSHWMKQPISFHKIKLTNNTLDQMGHIILHSMHKYQPRFHIVR----------- 229

  Fly   337 KELQDLDHK------TYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDP-ME 394
              .||:..:      ::.||||:|..||||||:.||:|||.:||||||||:....:..||.. ::
 Frog   230 --AQDVFSRRWGGCSSFTFPETLFLTVTAYQNEKITQLKIQTNPFAKGFREDGMKSKRDRSTRVK 292

  Fly   395 ALLLEQQLRSPLRLFPDPLMQQFAAQGD--------PSSMALFEKARQHLQMFGGNSPYAQLMMP 451
            ..::|          |:...::|..:|:        |....|.|:    |.:..|
 Frog   293 RKVIE----------PEEEEEEFQPEGECKRPLYTGPCDSTLSEE----LDIGRG---------- 333

  Fly   452 QMYQAAAAAAGPPPPPPGLGAFHMF----------QQQWPQLTAGFLASANQQAAAAQAAAQAQA 506
                     .|.|.|.|.. :||..          |...|.||      |||:..||...:....
 Frog   334 ---------LGIPLPSPDC-SFHPITPPSRTPPSTQTPNPSLT------ANQEQGAALEMSSQTP 382

  Fly   507 QAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRF-------------SP--YQLP 556
            :....||..:....||....:..|..|..........|...||.             ||  |::.
 Frog   383 ETFLQAAGQSYPEQPPVRGGSLYPCPTDGHGAQNQRHPLSVQRLPQAFQGLQESLGNSPGEYKIY 447

  Fly   557 GGQ-------GPPSSAAGSPPAVNAS 575
            ||.       .|||.|..  |:|..|
 Frog   448 GGDVGCGGDFAPPSCAVA--PSVRPS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	99/201 (49%)
tbx6	NP_001007995.1	T-box_TBX6	96..278	CDD:410322	98/200 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..318		8/51 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..418		22/110 (20%)