DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mid and vegt

DIOPT Version :9

Sequence 1:	NP_001260096.1	Gene:	mid / 33770	FlyBaseID:	FBgn0261963	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_988858.1	Gene:	vegt / 394452	XenbaseID:	XB-GENE-1033829	Length:	455	Species:	Xenopus tropicalis

Alignment Length:	511	Identity:	152/511 - (29%)
Similarity:	216/511 - (42%)	Gaps:	132/511 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 NVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSC 178
            |...:.|.|.|.:....|       ||.:|..:.|....|..::||         ...|..||:
Frog     3 NCCQEHRLSAGHLEPETS-------SSCASDVKSSPDMDSVSSQDS---------LYLPNSVGA- 50

  Fly   179 NCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDII 243
                      .||.:.||.:||..||||||||:||||.|..::...|    :.|..:|.:|:|.:
Frog    51 ----------SLEDQVLWAQFHQEGTEMIITKSGRRMLPQCKIRLFG----LHPYAKYMLLVDFV 101

  Fly   244 PMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQ 308
            |:|:  :||.::::.|..||||:|.||.|.|.|||||.......|..|.|:|:|||||.:|:.|.
Frog   102 PLDN--FRYKWNKNQWEAAGKAEPHPPCRTYVHPDSPAPGAHWMKDAICFQKLKLTNNTLDQQGH 164

  Fly   309 IVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSN 373
            |:|:|||||:||.|:|:   ...:.::|..|.    :.:.||||.|||||||||:.||||||:.|
Frog   165 IILHSMHRYKPRFHVVQ---SDDMYNSPWGLV----QVFSFPETEFTAVTAYQNEKITKLKINHN 222

  Fly   374 PFAKGFRDSSR-------------------------------LTDFDRDPMEALLLEQQLRSPLR 407
            |||||||:..|                               ::||   |....:.|:.:..|..
Frog   223 PFAKGFREQERRHKRDDVLKTLQQSPSKRQKRKKWEDSPEAEISDF---PKATRVKEESIMDPAG 284

  Fly   408 LFPDPLMQQFAAQG----------------DPSSMALF------EKARQHLQMFGGNSPY----- 445
            ::.:.:....|.||                .|||.:.|      .::.|||     :|||
Frog   285 VYQNWVSDHEANQGLTPHSPESEGANQEQQVPSSSSNFYNRNPYRRSSQHL-----SSPYDLGEP 344

  Fly   446 -AQLMMPQMYQAAAAAAGPPPPPPGLGAFHMF--QQQWPQLTAGFLASANQQAA--------AAQ 499
             ::.:.|.:      |..|...|..|...|:.  |......|.|...|...|..        :..
Frog   345 SSRRLTPDV------ATVPDSDPDSLAVLHVIPTQNSTQDRTCGVNFSMEAQMKQPLRGAMYSPY 403

  Fly   500 AAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFS--PY 553
            .|.|....||.....|.....|       |..||......|......:.::|  ||
Frog   404 GAEQWMVPAQGQYRPMGYTAYP-------TDLSTQGAVAHPHSGMSDWSQYSLFPY 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	94/198 (47%)
vegt	NP_988858.1	TBOX	51..234	CDD:238106	94/195 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..276		5/49 (10%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	295..360		16/75 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910