Protein Alignment mid and tbx1

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_005168668.1
• Gene: tbx1 / 368206
• ZFINID: ZDB-GENE-030805-5
• Length: 519
• Species: Danio rerio
• Alignment Length: 608
• Identity: 185/608 - (30%)
• Similarity: 265/608 - (43%)
• Gaps: 169/608 - (27%)

  Fly    15 AAPAAPNASGQTTTTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVDVDVVDCS 79
            ::|.:|.|:.                ||||.:::..|.:...:..:.|:.:..:     .|.:||
Zfish     4 SSPLSPKANA----------------FSIACLISARDQAGNTTFDKHATSLDKQ-----AVQNCS 47

  Fly    80 --------------DAEEPPTKARRLNH------------------------------HQHHQHH 100
                          :|...|. ..:|:|                              :.||:..
Zfish    48 RYIKMHYSTVTREMEAISSPW-LTQLSHFCDVAAFTTSSLSSLNTPGSYHLSPSPGDPYSHHESQ 111

  Fly   101 -------QHHHNNNNNNNNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSPGTED 158
                   ||.:|.:.:|:               || |.|:....||:.||....|||.::
Zfish   112 FEPCPAAQHAYNYSGSNS---------------AQ-APAQGDSGTSNCSSSSSSSTPNKT----- 155

  Fly   159 SEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSF 223
                    .|:|.||:..         :...||.|.|||.|:.||||||:||.|||||||.:|..
Zfish   156 --------LVKKNPKVAN---------INVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKI 203

  Fly   224 SGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRK 288
            .|    :.|...|.:|||.:|:|.||||||:|.|:||||||||||.|.|::.|||||.......|
Zfish   204 FG----MDPMADYMLLMDFLPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMK 264

  Fly   289 QVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETV 353
            |::||:|:|||||.:|.||.|:||||||||||.|:|.:...:......:|    ::||:||.||.
Zfish   265 QIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEE----NYKTFVFEETR 325

  Fly   354 FTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRD----PMEALLLEQQLRSPLRLFPDPLM 414
            |||||||||..||:|||.||||||||||... .|:.|:    .::.:....:.|:|:...|
Zfish   326 FTAVTAYQNHRITQLKIASNPFAKGFRDCDP-EDWPRNHRPGSLQIMSAFARTRNPMSSPP---- 385

  Fly   415 QQFAAQGDPSSMALFEKARQHLQMFGGN----SPYAQLM-------MPQM--YQAAAAAAGPPPP 466
            ||...:.:.|       .|::.:...||    .|..|||       :|.:  ..|....|||..|
Zfish   386 QQNGTEKEDS-------RREYDRDPSGNPLHSDPTHQLMSRVLSPALPVLGGLHAVPLTAGPRSP 443

  Fly   467 PPGL---------GAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPP 522
            |..|         ...|....::|.....:|            .|:.:.....:.:.......|.
Zfish   444 PHELRLDGHPQPPDTLHHHPYKYPATYEHYL------------GAKTRPSPYPSPSIRGHGYHPH 496

  Fly   523 PPPTASTPSSTSSGSPSPDMRPR 545
            ..||.:...|.:|...:.|..||
Zfish   497 MNPTTANMYSATSAPTNYDYGPR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	112/195 (57%)
tbx1	XP_005168668.1	T-box_TBX1_10-like	165..353	CDD:410313	111/204 (54%)