Protein Alignment mid and TBX10

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_011543294.1
• Gene: TBX10 / 347853
• HGNCID: 11593
• Length: 430
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 164/453 - (36%)
• Similarity: 212/453 - (46%)
• Gaps: 103/453 - (22%)

  Fly   122 SGGAVAQTASAESQLNTSSTSSQGRCSTP-PQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKP 185
            |.|......|....|.|:|:..:.|..:| |..|.|..:..:...||..:.||          .|
Human    51 SAGLGILAPSETYPLPTTSSGWEPRLGSPFPSGPCTSSTGAQAVAEPTGQGPK----------NP 105

  Fly   186 ----VQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMD 246
                |...||.|.||:.|:.||||||:||.||||||..:|...|    :.....||:|||.||:|
Human   106 RVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILG----MDSLADYALLMDFIPLD 166

  Fly   247 SKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVL 311
            .||||||:|.||||||||||||.|.|::.|||||.......:|::||:|:|||||.:|.||.|:|
Human   167 DKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIIL 231

  Fly   312 NSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFA 376
            |||||||||.|:|.:...:......:|    :.|:::|.||.|||||||||..||:|||.|||||
Human   232 NSMHRYQPRFHVVFVDPRKDSERYAQE----NFKSFIFTETQFTAVTAYQNHRITQLKIASNPFA 292

  Fly   377 KGFRDSSRLTDFDRDPMEAL-LLEQQLRSPLRLFPDPLMQQFAAQGDPSSMALFEKARQHLQMFG 440
            ||||:|    |.|..|:... ||....||...|.|..|......:.||:
Human   293 KGFRES----DLDSWPVAPRPLLSVPARSHSSLSPCVLKGATDREKDPN---------------- 337

  Fly   441 GNSPYAQLMMPQMYQAAAAAAGPP--------PPPPGLGAFHMFQQQWPQLTAGFLASANQQAAA 497
                          :|:|:.:..|        |||..|                 ||.|..:...
Human   338 --------------KASASTSKTPAWLHHQLLPPPEVL-----------------LAPATYRPVT 371

  Fly   498 AQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQG 560
            .|:.      ...|.:.:...||.|.|            .|.|::|..:.|...|  ||.|.|
Human   372 YQSL------YSGAPSHLGIPRTRPAP------------YPLPNIRADRDQGGLP--LPAGLG 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	112/202 (55%)
TBX10	XP_011543294.1	TBOX	110..300	CDD:238106	111/201 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740