Protein Alignment mid and Eomes

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001414322.1
• Gene: Eomes / 316052
• RGDID: 1359706
• Length: 708
• Species: Rattus norvegicus
• Alignment Length: 684
• Identity: 165/684 - (24%)
• Similarity: 236/684 - (34%)
• Gaps: 197/684 - (28%)

  Fly     4 GSHPYLCNGVPAAPAAPNASGQTTTTASKSAAGSATDFSIAAIMA-------REDASSRESSIRS 61
            ||.|  |.   |..|.|..:|.....|..|.|.:...|..|:.:|       |:.:...|..:.|
  Rat    68 GSLP--CQ---AGSAEPAGAGAGAPAAMLSDADAGDTFGSASAVAKPGPPDGRKGSPCAEEELPS 127

  Fly    62 ASPISVEDEVDVD-------------------VVDCSDAEEPPTKARRLNHHQHHQHHQHHHNNN 107
            |:..:......:|                   ...||..:.|......            |.:..
  Rat   128 AATAAATARYSMDSLSSERYYLPSPGPQGSELAAPCSLFQYPAAAGAA------------HGSVY 180

  Fly   108 NNNNNNNVAHKSRNSGG----AVAQTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPV 168
            ..:|.....:.|....|    ||...|.::....|.|.|..|........||         ..|.
  Rat   181 PASNGARYPYGSMLPPGGFPAAVCPPARSQFGPATGSGSGAGSSGGGAGGPG---------GYPY 236

  Fly   169 QKAPKIVG-------SCNCDDLKPV---------QCHLETKELWDRFHDLGTEMIITKTGRRMFP 217
            .:...:.|       :.:|..|..:         ..:|..:.||.:||...|||||||.||||||
  Rat   237 GQGSPLYGPYAGTSAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFP 301

  Fly   218 TVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPA-RLYAHPDSPF 281
            .:..:.:|    :.|...|.|.::::..|...:|  :....|:..||||..... ::|.||:||.
  Rat   302 FLSFNING----LNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGKADNNMQGNKMYVHPESPN 360

  Fly   282 SCEALRKQVISFEKVKLTNNEMDKNG---QIVLNSMHRYQPRIHLVRLSH-GQSIPSNPKELQDL 342
            :.....:|.|||.|:|||||:...|.   .|||.|:|:||||:|:|.::. |....:.|.:.|
  Rat   361 TGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ-- 423

  Fly   343 DHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD----------SSRLTDFDRD-PMEAL 396
               |:.|.||.|.|||||||..||:||||.|||||||||          :.|||....| |....
  Rat   424 ---TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQ 485

  Fly   397 LLEQQLRSPLRLFPDPLMQQFAAQGDPSSMALFEKARQHLQMFGGNSPYAQ---LMMPQMYQAAA 458
            ::..........||:|                |.......:.:.|.....|   |:.||.   :.
  Rat   486 IVPGGRYGVQNFFPEP----------------FVNTLPQARYYNGERTVPQTNGLLSPQQ---SE 531

  Fly   459 AAAGPPPPPPGLGAFHMFQQQW-----------------------------------PQLTA--- 485
            ..|.||             |:|                                   |..|:
  Rat   532 EVANPP-------------QRWLVTPVQQPVTNKLDIGSYESEYSSSTLLPYGIKSLPLQTSHAL 583

  Fly   486 GFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPP----------------------PPPTAS 528
            |:.......|.|......|..:..||.....:..:||                      .||:..
  Rat   584 GYYPDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSPPVFPEDQLAKEKVKEEISSSWVETPPSIK 648

  Fly   529 TPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPP 562
            :..|..||..:...:.:   |.||.....|..||
  Rat   649 SLDSNDSGVYNSACKRK---RLSPTTSSNGNSPP 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	86/219 (39%)
Eomes	NP_001414322.1	None