Protein Alignment mid and Tbx18

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001101643.1
• Gene: Tbx18 / 315870
• RGDID: 1309856
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 204/616 - (33%)
• Similarity: 270/616 - (43%)
• Gaps: 170/616 - (27%)

  Fly    41 FSIAAIMAREDASSRESSIRSASPISVEDEVDVDVVD-------------CSDAEE---PPTKAR 89
            ||:.|::..|.....:...|..:.......||    |             |::|:|   ||..|
  Rat    20 FSVEALIGAEKQQQLQKKRRKLATEEAAGAVD----DAGCSRGGGAREHRCTEADEDPAPPPPA- 79

  Fly    90 RLNHHQHHQHHQHHHNNNNNNNNNNVAHKSRNSGGAVAQTAS-AESQLNTSSTSSQGRC------ 147
                                            :|.|.....| .:::.:.:|....|.|
  Rat    80 --------------------------------AGSASGPARSCTDAERSCASRGPAGSCEDGFLQ 112

  Fly   148 -STPPQSPGTEDSEERL-------TPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGT 204
             ::|..|||.......:       ||.|..:||::              .|:..|||.|||::||
  Rat   113 GASPLASPGGSPKGSPVPGLARPGTPLPAPQAPRV--------------DLQGAELWKRFHEIGT 163

  Fly   205 EMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAP 269
            ||||||.||||||.:||..||    :.|..:|.:.|||:|:|:|||||.||.|.|:|||.||...
  Rat   164 EMIITKAGRRMFPAMRVKISG----LDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPV 224

  Fly   270 PARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSI-P 333
            |.|:|.|||||.|.|...:|||||:|:||||||:|..|.|:|:|||:||||:|::|...|..: |
  Rat   225 PPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHIIRKDCGDDLSP 289

  Fly   334 SNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLL 398
            ..|....: ..|.:.|||||||.|||||||.||:||||.||||||||||.|    :|..:|||:.
  Rat   290 IKPVPSGE-GVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGR----NRMGLEALVE 349

  Fly   399 EQQL-RSPLRLFPDPLMQQFAAQGDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAG 462
            .... |..||......:.....||:.||.||       |...|...|.|.   |.:...::.::
  Rat   350 SYAFWRPSLRTLTFEDIPGIPKQGNTSSSAL-------LPGTGNGVPAAH---PHLLSGSSCSS- 403

  Fly   463 PPPPPPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANR-------T 520
                    .|||: .....||.:  :|.|:..|.|....|   ....:.:.|...||       |
  Rat   404 --------PAFHL-GPNTSQLCS--MAPADYSACARSGLA---LNRYSTSLAETYNRLTNQSSET 454

  Fly   521 PPPPPTASTPSSTSSGSPSPDMR-----------PR-----QYQRFSP---YQLPGGQGPPSSAA 566
            ..||   .|||..|..|||.:|.           |:     |....||   |.:|.    |||.|
  Rat   455 FAPP---RTPSYVSVSSPSVNMSMGGTDGDTFSCPQTSLSMQISGMSPQLQYIIPS----PSSNA 512

  Fly   567 ----------------GSPPAV---NASRSP 578
                            .||.|:   |.|.||
  Rat   513 FAANQTHQGSYNTFRLHSPCALYGYNFSTSP 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	115/199 (58%)
Tbx18	NP_001101643.1	TBOX	145..340	CDD:238106	117/217 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810