Protein Alignment mid and Tbx20

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001388019.1
• Gene: Tbx20 / 315497
• RGDID: 1309396
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 199/498 - (39%)
• Similarity: 270/498 - (54%)
• Gaps: 116/498 - (23%)

  Fly    27 TTTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVDVDVVDCSDAEEPPTKARRL 91
            |.:.....:..|..|||||:|:......:|::..:..|:.       ..|:.|...:|..:...|
  Rat     4 TASPKPQLSSRANAFSIAALMSSGGPKEKEAAENTIKPLE-------QFVEKSSCAQPLGELTSL 61

  Fly    92 NHHQHHQHHQHHHNNNNNNNNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTP--PQSP 154
            :                       ||.....||.             ||.||...|:.|  |.:|
  Rat    62 D-----------------------AHAEFGGGGG-------------SSPSSSSLCTEPLIPTTP 90

  Fly   155 GTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTV 219
                               |:.|   :::..:.|.||||||||:||:|||||||||:|||||||:
  Rat    91 -------------------IIPS---EEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTI 133

  Fly   220 RVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCE 284
            ||||||    :.|..:|.|||||:|:|:||||||||||:|||||||||..|||||.||||||:.|
  Rat   134 RVSFSG----VDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGE 194

  Fly   285 ALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLV-RLSHGQSIPSNPKELQDLDHKTYV 348
            .|.||::|||||||||||:|::|.|:|||||:||||:|:: :..|..|:    ..|:..:.:|::
  Rat   195 QLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASL----LNLKSEEFRTFI 255

  Fly   349 FPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQ-LRSPLRLFPDP 412
            |||||||||||||||||||||||||||||||||||||||.:|:.:|:|:.:.. .|||:|.:.:.
  Rat   256 FPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGEE 320

  Fly   413 LMQQFAAQGDPSSMALFEKAR-----------------QHLQ-------------------MFGG 441
            .:....:|..|:..:.|..:.                 ||.|                   :.|.
  Rat   321 DVLGEESQTTPNRGSAFTTSDNLSLSSWVSSSSSFPGFQHPQPLTALGTSTASIATPIPHPIQGS 385

  Fly   442 NSPYAQLMMPQMYQAAAAA---AGPPPPPPGLGAFHMFQQQWP 481
            ..||::|.||....|.|::   :||..|...:..:|.:.||.|
  Rat   386 LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGP 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	136/196 (69%)
Tbx20	NP_001388019.1	T-box_TBX20-like	100..289	CDD:410319	136/196 (69%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<320..>408	CDD:476819	14/87 (16%)