Protein Alignment mid and bi

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 823
• Identity: 215/823 - (26%)
• Similarity: 291/823 - (35%)
• Gaps: 354/823 - (43%)

  Fly    12 GVPAAPAAPNASGQTTTTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVDVDVV 76
            |...:|.:.::|..||||::.:                 ::||..::..|.
  Fly    90 GAQLSPQSNHSSSNTTTTSNTN-----------------NSSSNNNNNNST-------------- 123

  Fly    77 DCSDAEEPPTKARRLNHHQHHQHHQHHHNNNNNN------------------------------- 110
                             |.::.:|.:::||||||
  Fly   124 -----------------HNNNNNHTNNNNNNNNNTSQKQGHHLSTTEEPPSPAGTPPPTIVGLPP 171

  Fly   111 ----NNNNVAHKSRNSGGAVAQ-----TASAESQLNTSSTSSQGRCSTPPQSP-----GTEDSEE 161
                |||:.:..|.||..|.|.     ||:..|....::....|....||.:|     ..:..::
  Fly   172 IPPPNNNSSSSSSNNSASAAAHPSHHPTAAHHSPSTGAAAPPAGATGLPPPTPPHHLQQQQQQQQ 236

  Fly   162 RLTPEPVQKAPK-------------------------------------------------IVGS 177
            ...|.|....|.                                                 ::.|
  Fly   237 HPAPPPPPYFPAAALAALAGSPAGPHPGLYPGGGLRFPPHHPGAHPHAHHLGSAYTTAEDVVLAS 301

  Fly   178 CNCDDLKPV------------------QCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFS 224
            .....|.|.                  :..||.|:||::||.|||||:|||:||:|||.::...|
  Fly   302 AVAHQLHPAMRPLRALQPEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVS 366

  Fly   225 GPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQ 289
            |    :....:|.:|:||:..|.  |||.:|.|.|:|||||||..|.|:|.|||||.:.|...::
  Fly   367 G----LDAKAKYILLLDIVAADD--YRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQK 425

  Fly   290 VISFEKVKLTNNEMDKNGQI---VLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPE 351
            |:||.|:|||||..||:|.:   :|||||:||||.||||.:....:|.:       ..:||||.|
  Fly   426 VVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYS-------TFRTYVFKE 483

  Fly   352 TVFTAVTAYQNQLITKLKIDSNPFAKGFRD-------------SSRLTDFDR------------- 390
            |.|.|||||||:.||:||||:|||||||||             |:|.:|.|:
  Fly   484 TEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAPL 548

  Fly   391 -----------DPMEALLLEQQ------------LRSPLRLFPDPLMQQFAAQGDPSSMALF--- 429
                       .|..|||..||            .:|||......|.|..|.|...:..|.|
  Fly   549 HLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGPPQSPLLPLSHSLQQMHAHQHSAALAAWFNHL 613

  Fly   430 ---------------------EKARQHLQ----------------MFGGNS-----PYAQLMMPQ 452
                                 :..|:.||                ..||::     |.:.....:
  Fly   614 AGAGAGASEHAAAAAANASAEDALRRRLQADADVERDGSDSSCSESVGGSTGGAFRPTSTGSPKE 678

  Fly   453 MYQAAAAAA------------------GPP------------P----PPPGLGAFHMFQQQWPQL 483
            ...||||||                  |||            |    |||.||..|
  Fly   679 AVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSPHLLPYLYPHGLYPPPHLGLLH--------- 734

  Fly   484 TAGFLASANQQAAA--------------AQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTS 534
                    |..|||              ||.|..||..|....|..||..||..|
  Fly   735 --------NPAAAAAMSPAGLNPGLLFNAQLALAAQHPALFGHAYAAAGHTPVSP---------- 781

  Fly   535 SGSPSPDMRPRQYQRFSPYQLPGGQGPPSSAAGSPPAVNASRS 577
                   ::..:..|||||.|||..|....|.  .|..||:||
  Fly   782 -------LQGLKSHRFSPYSLPGSLGSAFDAV--TPGSNANRS 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	104/229 (45%)
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:337907	3/57 (5%)
		T-box_TBX2_3-like	326..513	CDD:410314	102/199 (51%)