Protein Alignment mid and Tbx4

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_006247098.1
• Gene: Tbx4 / 303399
• RGDID: 1309057
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 160/543 - (29%)
• Similarity: 232/543 - (42%)
• Gaps: 129/543 - (23%)

  Fly   108 NNNNNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAP 172
            :|:||.||                .|..|.|...|.....|.|.|  |.:          |..|.
  Rat    25 SNSNNTNV----------------PEPALATPGLSGTALSSPPGQ--GAD----------VAAAA 61

  Fly   173 KIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYA 237
            ....:.....::.::..|..||||.:||:.||||||||.||||||:.:|..:|    :.|..:|.
  Rat    62 AAAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTG----MNPKTKYI 122

  Fly   238 VLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNE 302
            :|:||:|.|..||::..::  |:|||||:||.|.|||.|||||.:.....:|::||:|:|||||.
  Rat   123 LLIDIVPADDHRYKFCDNK--WMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNH 185

  Fly   303 MDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITK 367
            :|..|.|:|||||:||||:|:|:.....:..|     ::....|:|||||.|.:||:|||..||:
  Rat   186 LDPFGHIILNSMHKYQPRLHIVKADENNAFGS-----KNTAFCTHVFPETSFISVTSYQNHKITQ 245

  Fly   368 LKIDSNPFAKGFRDS-------SRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQFAAQGDPSS 425
            |||::||||||||.|       :||...:...:...::.|:|.|          .|.:|:.|.|.
  Rat   246 LKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLVS----------SQLSAKPDVSP 300

  Fly   426 MALFEKARQHLQMFGGNSPYAQLMMPQ-------------------MYQAAAAAAGPPPP----- 466
            :....:|.||.|...|.........||                   :.:.|.:|.....|
  Rat   301 LHSTHQALQHYQYENGAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRRADSARHLDLPCKRSY 365

  Fly   467 ---PPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPP---- 524
               |..:|..|.|:.. |......|:.:.......:.|....:.....|...|.:..||||
  Rat   366 LETPSSVGDDHYFRSP-PPYDQQMLSPSYCSEVTPREACMYSSSGPEIAGVSAVDDLPPPPLSCN 429

  Fly   525 ------------------------PTAST--------PSSTSSGSPSPDMRPRQYQRFSPYQL-- 555
                                    ||..|        |.:..|..|..:.....|.:.|..|:
  Rat   430 MWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPIAAQSAQPPGNAHFSVYNQLSQSQVRE 494

  Fly   556 -------PGGQGPPSSAAGSPPA 571
                   |..:|.|:.....||:
  Rat   495 RGPSASFPRERGLPAVCERKPPS 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	98/195 (50%)
Tbx4	XP_006247098.1	T-box_TBX4_5-like	75..259	CDD:410315	97/194 (50%)