Protein Alignment mid and tbx2b

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_571126.1
• Gene: tbx2b / 30253
• ZFINID: ZDB-GENE-990726-27
• Length: 687
• Species: Danio rerio
• Alignment Length: 602
• Identity: 181/602 - (30%)
• Similarity: 236/602 - (39%)
• Gaps: 242/602 - (40%)

  Fly   159 SEERLTP-EPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVS 222
            |.:.|.| |.|:..||:.              ||.|:|||:||.|||||:|||:||||||..:|.
Zfish    80 SLKSLEPEEEVEDDPKVT--------------LEAKDLWDQFHKLGTEMVITKSGRRMFPPFKVR 130

  Fly   223 FSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALR 287
            .:|    :....:|.:||||:..|..||:  :|.|.|:|||||||..|.|:|.|||||.:.|...
Zfish   131 ING----LDKKAKYILLMDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWM 189

  Fly   288 KQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPET 352
            .:.::|.|:|||||..||:|..:|||||:||||.|:||.:....:|.:       ..:|||||||
Zfish   190 AKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYS-------TFRTYVFPET 247

  Fly   353 VFTAVTAYQNQLITKLKIDSNPFAKGFRDS--------SRLT-----------DFDRDPMEALLL 398
            .|.|||||||..||:||||:|||||||||:        .:||           ..|||..::...
Zfish   248 DFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRMYEDQCKVDRDGADSDAS 312

  Fly   399 EQQ-------------LRSPLRL------------------------------------------ 408
            ..:             :.||||.
Zfish   313 SSEPTTGRDAGHSPGPVSSPLRFNRGSRDDKTCTDSEHEMDHQNDRCGGSSSPAPKPSSPFRSRS 377

  Fly   409 ---------------FPD----------------------------------------------- 411
                           :||
Zfish   378 EDWGREKPIAEKKDDYPDSRKTSDSIFSIRNLEKDKLESRSRKDTDSSKKDTENSGISGSKDSFS 442

  Fly   412 PLMQQ------FAAQGDPSSMALFEKARQHLQMFGG--NSPYAQLMMPQMYQ------------- 455
            |||.|      |.| |...|:||   :..|.|.|..  |:....|..|..:.
Zfish   443 PLMVQTESPSHFGA-GHLQSLAL---SGLHSQQFFNPLNTGQPLLFHPGQFAMAPGAFSAMGMGH 503

  Fly   456 --AAAAAAG--------------PPPPPPGLGAFHMFQ-----QQWPQLTAG--FLASANQQAAA 497
              |:.:.||              .|.|.|    ||:.|     |..|..|.|  |.......|||
Zfish   504 LLASVSGAGGLENGSLSAQGTGSTPSPFP----FHLSQHMLASQGIPMPTFGGLFPYPYTYMAAA 564

  Fly   498 AQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSP--SPDMRPRQYQRFSPYQLPGG-- 558
            |           |||:|:         |.:|:.:|:.|.:|  |...|||  .||:|||||..
Zfish   565 A-----------AAASAL---------PASSSTASSLSRNPFLSSSTRPR--LRFNPYQLPVSIP 607

  Fly   559 QGPPSSAAGSPPAVNAS 575
            |.......|.|..:|.|
Zfish   608 QSTNLLTTGLPSGLNPS 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	103/195 (53%)
tbx2b	NP_571126.1	T-box_TBX2_3-like	95..276	CDD:410314	103/207 (50%)
		TBX	294..361	CDD:432659	7/66 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..452		13/148 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..687		4/14 (29%)