Protein Alignment mid and tbx4

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_570989.3
• Gene: tbx4 / 30070
• ZFINID: ZDB-GENE-991124-5
• Length: 543
• Species: Danio rerio
• Alignment Length: 582
• Identity: 172/582 - (29%)
• Similarity: 244/582 - (41%)
• Gaps: 187/582 - (32%)

  Fly   121 NSGGAVAQT------ASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCN 179
            :.|..|||:      ||..|.|...:|.|..:.:.|.||
Zfish    11 DEGMTVAQSGGRPELASDSSHLGLPTTPSNPQNNEPDQS-------------------------- 49

  Fly   180 CDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIP 244
            .:::|.|   |..:|||.:||:.||||||||.||||||:.:|..:|    :.|..:|.:|.||:|
Zfish    50 IENIKVV---LHDRELWKKFHEAGTEMIITKAGRRMFPSYKVKVTG----MNPKTKYILLTDIVP 107

  Fly   245 MDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQI 309
            .|..||::..::  |:|||||:||.|.|||.|||||.:.....:|::||:|:|||||.:|..|.|
Zfish   108 ADDHRYKFCDNK--WMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHI 170

  Fly   310 VLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNP 374
            :|||||:||||:|:|:.....:..|     ::..:.|:||.||.|.:||:|||..||:|||::||
Zfish   171 ILNSMHKYQPRLHIVKADENNAFGS-----KNTAYCTHVFHETAFISVTSYQNHKITQLKIENNP 230

  Fly   375 FAKGFRDS-------SRLTDFDRDPMEALLLEQQLRSP------------LRLFP---------- 410
            ||||||.|       |||...|...:...::.|:|.|.            |...|
Zfish   231 FAKGFRGSDEGDLRVSRLQGKDYPVISKNMVRQRLISSHGHLSGKLSAGVLSSHPQVLSHYQYDS 295

  Fly   411 ----------DPLMQQFAAQGDPSSMALFEKAR---QHLQMFGGNSPYAQ-----------LMMP 451
                      :.|...|.:..:||.:....|.|   :||:: |...||..           ...|
Zfish   296 GVPLPNSDSQEALSNSFTSSREPSLLYHCFKHRDNPRHLEL-GCKRPYLDTTSSAVSEEHYFRSP 359

  Fly   452 QMYQA--------------------------AAAAAG----PPP-----------PPPGLGAFHM 475
            ..|.:                          ...|.|    |.|           |.|..|...:
Zfish   360 PSYDSPLLSHPYCNEALGSREACMYGGLEGEGGGAVGTDDLPAPSLNCNMWASVQPYPRYGMQTV 424

  Fly   476 FQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPP----------PPTASTP 530
            ...|:...||.|    |..|:||...:......|      ..:.|||.          |||.|:.
Zfish   425 EAMQYQPFTAHF----NSTASAASMVSHHSPSMQ------RPHPTPPDLVTFTTQRVLPPTPSSA 479

  Fly   531 SSTSSGSPSPDM-----------RPRQYQR-FSPYQLPGGQGPPSSAAGSPPAVNASRSPAH 580
            |::.|||...|.           .|.:.|| |:.|           :..||   .::|.||:
Zfish   480 STSPSGSGHHDRAHSSLFHRKAGSPLRSQRDFTGY-----------STHSP---TSTREPAY 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	97/195 (50%)
tbx4	NP_570989.3	None