DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mid and Mga

DIOPT Version :9

Sequence 1:	NP_001260096.1	Gene:	mid / 33770	FlyBaseID:	FBgn0261963	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	XP_006499750.1	Gene:	Mga / 29808	MGIID:	1352483	Length:	3091	Species:	Mus musculus

Alignment Length:	300	Identity:	110/300 - (36%)
Similarity:	162/300 - (54%)	Gaps:	36/300 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 DSEERLTPE--PVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVR 220
            |:...|:.|  |.:...||....:| .:..:...|:...:|:.||:..||||:||.||||||..|
Mouse    46 DARALLSRESSPGKSKEKICLPADC-TVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCR 109

  Fly   221 VSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEA 285
            ...:|    :....:|.::|||.|:||  :||.::...|..:|||:|....|::.||:||.:...
Mouse   110 YWITG----LDSNLKYILVMDISPVDS--HRYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHY 168

  Fly   286 LRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFP 350
            ...|.:||.|:|||||.:|:.|.|:|:|||||.||:|||.......:    .:|......|:.||
Mouse   169 WMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKATEV----IQLNGPGVHTFTFP 229

  Fly   351 ETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQ----LRSP---LRL 408
            :|.|.|||||||..||:||||.|||||||||....:...|:..:....:|:    ..||   :||
Mouse   230 QTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLSSKPQREGKQRNSSDQEGNSVSSSPAHRVRL 294

  Fly   409 FP-----------DPLMQQFAAQGDPSSMALFEKARQHLQ 437
            ..           ||:::...|    ||::| |||..:::
Mouse   295 TEGEGSEIHSGDFDPVLRGHEA----SSLSL-EKAPHNVK 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	88/198 (44%)
Mga	XP_006499750.1	TBOX	74..264	CDD:238106	88/199 (44%)
		DUF4801	1038..1080	CDD:374336
		DUF5585	<1510..>1811	CDD:375359
		Atrophin-1	1729..>2023	CDD:367360
		bHLHzip_MGA	2452..2516	CDD:381481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750