Protein Alignment mid and Tbx3

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_035665.2
• Gene: Tbx3 / 21386
• MGIID: 98495
• Length: 741
• Species: Mus musculus
• Alignment Length: 669
• Identity: 190/669 - (28%)
• Similarity: 254/669 - (37%)
• Gaps: 259/669 - (38%)

  Fly   124 GAVAQ------TASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDD 182
            ||:|:      ..:||:.:..||...|... .|.::...|        |.|:..||:
Mouse    58 GALAKPIMDQLVGAAETGIPFSSLGPQAHL-RPLKTMEPE--------EDVEDDPKV-------- 105

  Fly   183 LKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDS 247
                  |||.|||||:||..||||:|||:||||||..:|..||    :....:|.:|||||..|.
Mouse   106 ------HLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSG----LDKKAKYILLMDIIAADD 160

  Fly   248 KRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNG----- 307
            .||:  :|.|.|:|||||||..|.|:|.|||||.:.|....:|::|.|:|||||..||:|
Mouse   161 CRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223

  Fly   308 ---------------QIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAV 357
                           |.:|||||:||||.|:||.:....:|.:       ..:||:||||.|.||
Mouse   224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYS-------TFRTYLFPETEFIAV 281

  Fly   358 TAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQ------ 416
            |||||..||:||||:|||||||||:.   :..|:..:.|.|:.     :|:|.:...::
Mouse   282 TAYQNDKITQLKIDNNPFAKGFRDTG---NGRREKRKQLTLQS-----MRVFEERHKKETSDESS 338

  Fly   417 --------FAAQGDPS------------------SMALFEKARQH-------------------- 435
                    ||....|:                  |.|..|...:|
Mouse   339 SEQAAFNCFAQASSPAVSIVGTSNLKDLCPSEAESDAEAESKEEHGPEACDAAKISTTTAEEPGR 403

  Fly   436 --------LQMF------------------------------------------GGNSPYA---- 446
                    .|:|                                          |...|.|
Mouse   404 DKGSPATRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADERRSPGREGPVATKVD 468

  Fly   447 --------QLMMPQMYQAAAAAAGPPPPPPGLG-----AFHMFQQQWP---------------QL 483
                    ....|...|..|.|.....|.||||     |...|....|               .:
Mouse   469 EARAIPAKDAFAPLSVQTDATAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSM 533

  Fly   484 TAGF-------------LASANQQAAAAQAAAQAQAQAQAAA----------AAMAANRTP---- 521
            .||.             ::.....|.|:.||||..:.|.||.          |:.....:|
Mouse   534 AAGMGPLLATVSGASTGVSGLESTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL 598

  Fly   522 -PPPPT-------ASTPSSTSSGSPSP-----DMRPRQYQRFSPYQLPG---------GQGPPSS 564
             |.|.|       |||.:::||....|     .||||  .|:|||.:|.         ....||.
Mouse   599 FPYPYTYMAAAAAASTAAASSSVHRHPFLNLNSMRPR--LRYSPYSIPVPVPDSSSLLATALPSM 661

  Fly   565 AAGSPP----AVNASRSPA 579
            |:.:.|    |...:.|||
Mouse   662 ASAAGPLDGKAAALAASPA 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	108/218 (50%)
Tbx3	NP_035665.2	T-box	105..305	CDD:366363	106/226 (47%)
		TBX	323..402	CDD:372213	9/78 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..469		9/99 (9%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831475
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740