Protein Alignment mid and Tbx15

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_033349.2
• Gene: Tbx15 / 21384
• MGIID: 1277234
• Length: 602
• Species: Mus musculus
• Alignment Length: 611
• Identity: 198/611 - (32%)
• Similarity: 274/611 - (44%)
• Gaps: 152/611 - (24%)

  Fly    42 SIAAIMAREDASSRESSIRSASPISVED--EVDVDVV--------DCSDAEEPPTKARRLNHHQH 96
            |..|:.:|..|.|.|:.|.|.....:.|  |..:|:.        ...|.::|.|
Mouse     7 SAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTDDPAT---------- 61

  Fly    97 HQHHQHHHNNNNNNNNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEE 161
              |....|.::.                   |:..::|::.|..||    ||.   |..|:.:..
Mouse    62 --HGLEPHPDSE-------------------QSTGSDSEVLTERTS----CSF---STHTDLASG 98

  Fly   162 RLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGP 226
            ...|.|...:          .::.:|..|:..:||.||||:||||||||.||||||.:||..:|
Mouse    99 AAGPVPAAMS----------SMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITG- 152

  Fly   227 LRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVI 291
               :.|..:|.:.|||:|:|:|||||.||.|.|:|||.||...|.|:|.||||..|.:...:||:
Mouse   153 ---LDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVV 214

  Fly   292 SFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSI-PSNPKELQDLDHKTYVFPETVFT 355
            ||:|:||||||:|..|.|:|:|||:||||:|::|......: |:.|..:.| ..||:.|||||||
Mouse   215 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGD-GVKTFNFPETVFT 278

  Fly   356 AVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQFAAQ 420
            .|||||||.||:||||.||||||||||.|    :|..:||                 :|:.:|..
Mouse   279 TVTAYQNQQITRLKIDRNPFAKGFRDSGR----NRTGLEA-----------------IMETYAFW 322

  Fly   421 GDPSSMALFEKARQHLQMFGGN---SPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQW-- 480
            ..|.....||......:..||:   ||...........|::....|...||   .||:....:
Mouse   323 RPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPP---TFHLAPNTFNV 384

  Fly   481 ----PQLTAGFLASANQQAAAAQAAAQA----------QAQAQAAAAAMAA-----NRTP----- 521
                .||....|:.....|.:..||.|:          :.|:..|:|...:     .|||
Mouse   385 GCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSETFMPQRTPSLISG 449

  Fly   522 -PPPPT--------------ASTPSS------------TSSGSP----SPDMRPRQYQRFS---P 552
             |.||:              .|.|:|            :||.||    ...|:...|..||   |
Mouse   450 IPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNP 514

  Fly   553 YQLPGGQGPPS-SAAGSPPAVNASRS 577
            |.|.|...|.| ..|.||..::||:|
Mouse   515 YNLYGYNFPTSPRLAASPEKLSASQS 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	111/196 (57%)
Tbx15	NP_033349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..95		14/89 (16%)
		T-box_TBX15-like	107..304	CDD:410324	110/211 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..369		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..444		4/18 (22%)