Protein Alignment mid and Tbx1

DIOPT Version :9

• Sequence 1: NP_001260096.1
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001360867.1
• Gene: Tbx1 / 21380
• MGIID: 98493
• Length: 529
• Species: Mus musculus
• Alignment Length: 473
• Identity: 171/473 - (36%)
• Similarity: 222/473 - (46%)
• Gaps: 101/473 - (21%)

  Fly   130 ASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKE 194
            |.|.....:|:..|:|        ||.  |.......||:|.||:..         |...||.|.
Mouse   112 APAPGAAGSSAAESEG--------PGA--SRAAAVKAPVKKNPKVAS---------VSVQLEMKA 157

  Fly   195 LWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAW 259
            |||.|:.||||||:||.|||||||.:|...|    :.|...|.:|||.:|:|.||||||:|.|:|
Mouse   158 LWDEFNQLGTEMIVTKAGRRMFPTFQVKLFG----MDPMADYMLLMDFVPVDDKRYRYAFHSSSW 218

  Fly   260 LVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLV 324
            |||||||||.|.|::.|||||.......||::||:|:|||||.:|.||.|:||||||||||.|:|
Mouse   219 LVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVV 283

  Fly   325 RLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFD 389
            .:...:......:|    :.||:||.||.|||||||||..||:|||.||||||||||... .|:.
Mouse   284 YVDPRKDSEKYAEE----NFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP-EDWP 343

  Fly   390 RDPMEALLLEQQLRSPLRLFPDPLMQQFAAQGDP---------SSMALFEKARQHLQMFG----G 441
            |:.....|              ||:..||...:|         |.....|..|:..:..|    |
Mouse   344 RNHRPGAL--------------PLVSAFARSRNPVASPTQPNGSDKDAAEARREFDRDSGPAALG 394

  Fly   442 NSPY-AQLMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQ 505
            ::.: .||:...:..|.....|..|.|.|.|..|                         :...|.
Mouse   395 DATHPPQLLARVLSPALPGPGGLVPLPGGSGGRH-------------------------SPPHAD 434

  Fly   506 AQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPG----GQGPPSSAA 566
            .:.:|..|:...:..|...|.|:......:.|     ||      :||.|||    |..|.:...
Mouse   435 LRLEAPGASEPLHHHPYKYPAAAYDHYLGAKS-----RP------APYPLPGLRGHGYHPHAHPH 488

  Fly   567 GSP-----PAVNASRSPA 579
            ..|     ||||.:.:.|
Mouse   489 AHPHHHHHPAVNPAAAAA 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	114/198 (58%)
Tbx1	NP_001360867.1	T-box	151..336	CDD:366363	111/192 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740