DRSC/TRiP Functional Genomics Resources

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Protein Alignment mid and Eomes

DIOPT Version :9

Sequence 1:NP_001260096.1 Gene:mid / 33770 FlyBaseID:FBgn0261963 Length:580 Species:Drosophila melanogaster
Sequence 2:NP_034266.2 Gene:Eomes / 13813 MGIID:1201683 Length:707 Species:Mus musculus


Alignment Length:454 Identity:129/454 - (28%)
Similarity:175/454 - (38%) Gaps:127/454 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   189 HLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYA 253
            :|..:.||.:||...|||||||.||||||.:..:.:|    :.|...|.|.::::..|...:|  
Mouse   272 YLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNING----LNPTAHYNVFVEVVLADPNHWR-- 330

  Fly   254 YHRSAWLVAGKADPAPPA-RLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNG---QIVLNSM 314
            :....|:..||||..... ::|.||:||.:.....:|.|||.|:|||||:...|.   .|||.|:
Mouse   331 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSL 395

  Fly   315 HRYQPRIHLVRLSH-GQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKG 378
            |:||||:|:|.::. |....:.|.:.|     |:.|.||.|.|||||||..||:||||.||||||
Mouse   396 HKYQPRLHIVEVTEDGVEDLNEPSKTQ-----TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKG 455

  Fly   379 FRD----------SSRLTDFDRD-PMEALLLEQQLRSPLRLFPDPLMQQFAAQGDPSSMALFEKA 432
            |||          :.|||....| |....::..........||:|                |...
Mouse   456 FRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQNFFPEP----------------FVNT 504

  Fly   433 RQHLQMFGGNSPYAQ---LMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQW-------------- 480
            ....:.:.|.....|   |:.||.   :...|.||             |:|              
Mouse   505 LPQARYYNGERTVPQTNGLLSPQQ---SEEVANPP-------------QRWLVTPVQQPVTNKLD 553

  Fly   481 ---------------------PQLTA---GFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTP 521
                                 |..|:   |:.......|.|......|..:..||.....:..:|
Mouse   554 IGSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSP 618

  Fly   522 P-----------------------PPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPP 562
            |                       ||...|..||.|....|...|    :|.||.....|..||
Mouse   619 PVFPEDQLAKEKVKEEISSSWIETPPSIKSLDSSDSGVYNSACKR----KRLSPSTPSNGNSPP 678

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
midNP_001260096.1 TBOX 185..384 CDD:238106 86/209 (41%)
EomesNP_034266.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 27..125
TBOX 269..462 CDD:238106 86/200 (43%)
T-box_assoc 484..705 CDD:292794 38/231 (16%)
Required for transcription activation. /evidence=ECO:0000250 592..707 21/91 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 642..689 14/41 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831487
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3585
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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