Protein Alignment mid and org-1

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_061505283.1
• Gene: org-1 / 1281834
• VectorBaseID: AGAMI1_011288
• Length: 782
• Species: Anopheles gambiae
• Alignment Length: 692
• Identity: 210/692 - (30%)
• Similarity: 302/692 - (43%)
• Gaps: 199/692 - (28%)

  Fly    22 ASGQTTTTASKSAAG-----------SATDF----SIAAI-----MAREDAS----SRESSIRSA 62
            |.|.|.|...:|.:.           :.|||    |.||:     :|.::.:    :.|:.|::|
Mosquito    21 AGGSTGTMLHESFSSLVGTMPSAVDLNGTDFLHHYSPAAVDYWNPVAYKNGTNPMKAMEACIQNA 85

  Fly    63 -----SPISVEDEVDVDVVDC-SDAEEPPTK----------ARRLNHHQHHQ-HHQHHHNNNNNN 110
                 :|:   ::|:...:.| |:::..|.:          |..||:..||| :|..|:||||:.
Mosquito    86 NKGQYNPL---EQVEQLSISCDSESQASPLEQPGVHGLHQAANNLNNLGHHQLNHDAHNNNNNSL 147

  Fly   111 NNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSP--------GTEDSEERLT--- 164
            ::|....:|||.|.....|.|.    :.|....:|..|:...||        |.|..:|..|
Mosquito   148 SSNKNLRESRNDGKMQRSTGSR----HKSRAGRRGAPSSHNSSPEVHEDSRTGMEVDQEECTRTD 208

  Fly   165 --PEPVQKAPKIVGSCNCDD--------------------------------------------- 182
              .|.|:.:.:..|.....|
Mosquito   209 EDEEDVEGSDEDTGGDGDGDGSRRASIIQNGSRQSQHQQQQSSTKQPGAPPTTTFASKKSPEMDK 273

  Fly   183 -----LKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDI 242
                 |......||.|.|||:||:.|||||:||.|||||||.:|...|    ::.|..|.::||.
Mosquito   274 PYHSSLASAVVVLEGKHLWDKFHEQGTEMIVTKAGRRMFPTFQVKVVG----LELAAEYLMIMDF 334

  Fly   243 IPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNG 307
            :|:|.||||||:|.|:|:|||||||..|.|:..|||||.:.....||.|||:|:|||||::|.||
Mosquito   335 VPLDDKRYRYAFHTSSWVVAGKADPISPPRISVHPDSPATGATWMKQTISFDKLKLTNNQLDDNG 399

  Fly   308 QIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQD-LDHKTYVFPETVFTAVTAYQNQLITKLKID 371
            .|:||||||||||:|:...:.     :..|:.:| |.|:|:|||||.||||||||||.:|:|||.
Mosquito   400 HIILNSMHRYQPRLHVCYFTR-----NGVKDEKDTLTHRTFVFPETSFTAVTAYQNQRVTQLKIV 459

  Fly   372 SNPFAKGFRD--------------------SSRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQ 416
            ||||||||||                    :.|.:.:.:|...|.:......|..|:........
Mosquito   460 SNPFAKGFRDNETNEESQERSAPAISDRLKNERSSSYKKDSEMATISTGTSCSSPRITSSSSTAT 524

  Fly   417 FAAQGD--PSSMALFEKA-RQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPPPPGL-----GAF 473
            .||...  .|.::|.:.| .||..:.     :.|..:..::.|..|     .|..|.     |..
Mosquito   525 AAATNTTAASVLSLHQSAHHQHTSLH-----HLQHHLQHLHSAPGA-----NPADGAVTSTDGHH 579

  Fly   474 HMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQ--------AAAAAMAANRTPPPPPTASTP 530
            |....|            :|||...|...|.|...|        ..|:.:..:.:|     .::|
Mosquito   580 HHPHHQ------------HQQAHLQQHQQQHQQHQQHHHNGTSGGLASLVPGHHSP-----LNSP 627

  Fly   531 SSTSSGSPSPDMRPRQYQRFSPYQL-PGGQGPPSSAAGSPPA 571
            :|:|.|..|          .|||.| |.|    :|:.|:|.|
Mosquito   628 ASSSGGGSS----------LSPYGLSPHG----ASSGGTPTA 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	113/216 (52%)
org-1	XP_061505283.1	None