Protein Alignment mid and Tbx10

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001001320.1
• Gene: Tbx10 / 109575
• MGIID: 1261436
• Length: 385
• Species: Mus musculus
• Alignment Length: 451
• Identity: 159/451 - (35%)
• Similarity: 209/451 - (46%)
• Gaps: 128/451 - (28%)

  Fly   139 SSTSSQGRCSTP-PQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDL 202
            :|||.:.|..|. |....|..:|.:...||..:.||      ...:..|...||.|.||:.|:.|
Mouse    23 TSTSWESRLGTRFPSGSCTMSTEAQAMAEPTGQGPK------NPRVSSVMVQLEMKPLWEEFNQL 81

  Fly   203 GTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADP 267
            |||||:||.|||||||.:|...|    :.....||:|||.||:|.||||||:|.|||||||||||
Mouse    82 GTEMIVTKAGRRMFPTFQVKILG----MDTLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADP 142

  Fly   268 APPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSI 332
            |.|.|::.|||||.......:|::||:|:|||||.||.||.|:||||||||||.|:|.:...:..
Mouse   143 ATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLMDDNGHIILNSMHRYQPRFHVVFVDPRKDS 207

  Fly   333 PSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALL 397
            ....:|    :.|::||.||.|||||||||..||:|||.|||||||||::
Mouse   208 ARYAQE----NFKSFVFTETQFTAVTAYQNHRITQLKIASNPFAKGFREA--------------- 253

  Fly   398 LEQQLRSPLRLFPDPLMQQFAAQGDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAG 462
                                    ||.|..:              :|...|.:|...:::.:
Mouse   254 ------------------------DPDSWPV--------------TPRPLLSIPARSRSSLS--- 277

  Fly   463 PPPPPPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTP------ 521
                              |.|..|                .|:.:...:.|:.:::|||
Mouse   278 ------------------PCLLKG----------------SAEREKDTSKASASSSRTPTQPHNQ 308

  Fly   522 --PPPPTASTPS--------STSSGSPSPDMRPRQYQRFSPYQLP-----GGQGPPSSAAG 567
              |.|.....|:        :...||||....||  .|.:||.||     |.|..|:.|||
Mouse   309 LLPAPDVLLAPATYRPLPYQNLYPGSPSRAGPPR--ARLAPYPLPNISTAGDQEDPTLAAG 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	113/195 (58%)
Tbx10	NP_001001320.1	T-box_TBX1_10-like	65..252	CDD:410313	112/194 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..310		6/42 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..359		12/32 (38%)