Protein Alignment mid and tbx21

DIOPT Version :10

• Sequence 1: NP_608927.2
• Gene: mid / 33770
• FlyBaseID: FBgn0261963
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_002940203.2
• Gene: tbx21 / 100496799
• XenbaseID: XB-GENE-479103
• Length: 561
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 174/645 - (26%)
• Similarity: 238/645 - (36%)
• Gaps: 206/645 - (31%)

  Fly    12 GVPAAPAAP--NASGQTTTTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVDVD 74
            |:...|..|  .::|:..:|......            ||...:..:|.|:..|.::::     .
 Frog    19 GMQGPPTVPPMKSAGELQSTVRLPGT------------ARLQKTDMQSIIKLQSKMTMQ-----S 66

  Fly    75 VVDCSDAEEPPTKARRLNHHQHHQHHQHHHNNNNNNNNNNVAHKSR---NSGGAV---------- 126
            :.|...|.|........|....|:....|    |.....|.|.:||   :||..|
 Frog    67 IKDAQSATELHGATETQNRTDLHRTMSKH----NTVEMPNGAMQSREELHSGADVQSLPTEQHKY 127

  Fly   127 AQTASAESQLN-TSSTSSQGR------CS-TPPQSP-GTE-------DSEERLTPEPVQKAPKI- 174
            .|:.|.|..|| |.|..|:.|      || |...|| |.|       |:|   .|.|:.....:
 Frog   128 CQSNSGEDNLNPTFSFPSRIRLLPSSSCSYTQEYSPEGAEAVNYSERDAE---LPYPLSLQHALP 189

  Fly   175 ----VGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADR 235
                .|:..|.....||..|....|||:||...|||||||.||||||.:....:|    :.|..:
 Frog   190 HTNPSGTPECQRSGKVQITLTNYSLWDKFHKHQTEMIITKQGRRMFPFLSFRVAG----LDPVAQ 250

  Fly   236 YAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPA-RLYAHPDSPFSCEALRKQVISFEKVKLT 299
            |.:.:|::..|...:|  |....|...|||:...|. |.|.|||||.:.....:|.:.|.|:|||
 Frog   251 YNLHVDVVLADQNHWR--YQGGKWTQCGKAEGNMPGNRTYQHPDSPNTGAHWMRQEVIFSKLKLT 313

  Fly   300 NNEMDKNG---QIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQ 361
            ||:...|.   .:||.|:|:||||.|:.|:..    |..|:.    ...:::||||.|.||||||
 Frog   314 NNKGASNNVSQMVVLQSLHKYQPRFHVTRVED----PGGPES----QSHSFIFPETQFIAVTAYQ 370

  Fly   362 NQLITKLKIDSNPFAKGFRDSSRL----TDFDR-DPMEALLLEQQLRSPL---RLFPDPLMQQFA 418
            |..||:||||.|||||||||...|    .:.:| .|...:.....|:.|:   |||.       .
 Frog   371 NADITQLKIDHNPFAKGFRDHCDLMCLTPNGERVSPSPPVRYTNYLQEPVPSARLFS-------V 428

  Fly   419 AQGDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQWPQL 483
            .|.:|.|..|                .:|.:.||:..       ||..|.|
 Frog   429 EQKEPPSWYL----------------SSQNIAPQLEY-------PPYDPAG-------------- 456

  Fly   484 TAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGS----------P 538
                                       ..||.|....|.|.|.:..|..|.:.:          |
 Frog   457 ---------------------------KMAAYAMKCYPQPSPLSYYPEHTLTSAWGGPAQYHPKP 494

  Fly   539 SPD----MRP-------------------------RQYQRFSPYQLPGGQGPPSSAAGSP 569
            ||.    :||                         .:.:|.|||          |:.|||
 Frog   495 SPAPLGWLRPLLEVQKKEEDSCAWGDTTTYAGYEDSKRRRLSPY----------SSDGSP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_608927.2	T-box_TBX20-like	186..382	CDD:410319	87/199 (44%)
tbx21	XP_002940203.2	T-box	204..390	CDD:469628	86/199 (43%)