DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mid and mga

DIOPT Version :9

Sequence 1:	NP_001260096.1	Gene:	mid / 33770	FlyBaseID:	FBgn0261963	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	XP_012824488.2	Gene:	mga / 100038161	XenbaseID:	XB-GENE-492360	Length:	3054	Species:	Xenopus tropicalis

Alignment Length:	343	Identity:	114/343 - (33%)
Similarity:	166/343 - (48%)	Gaps:	74/343 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 QSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPV----------------QCH-------LETK 193
            ||.|....||.:          :|.:.:...:.||                :|.       |:..
Frog    29 QSQGNGKKEEGI----------VVANRDVSSVAPVMSSGHDKSKSKTFLSAECKSGNITVTLDNN 83

  Fly   194 ELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSA 258
            .:|:.|:...|||::||.||||||..|...||    :.|..:|.::|||.|||:  :||.::...
Frog    84 NMWNEFYRCSTEMVLTKQGRRMFPYCRYWISG----LDPYQKYILVMDISPMDN--HRYKWNGKW 142

  Fly   259 WLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHL 323
            |...||::|....|::.||:||.:.:....|.:||.|:|||||.:|:.|.|:|:|||||.||:|:
Frog   143 WEAGGKSEPHVLGRVFIHPESPSTGQYWMHQPVSFYKLKLTNNILDQEGHIILHSMHRYLPRLHV 207

  Fly   324 VRLSHGQSIPSNPK----ELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD--- 381
            |        |:|..    :|...|..|:.||:|.|.|||||||..||:||||.||||||||:
Frog   208 V--------PANQSTEVIQLNGPDVHTFTFPQTEFIAVTAYQNFQITQLKIDCNPFAKGFREGAM 264

  Fly   382 --------SSRLTDFDRDPM--------EALL-LEQQLRSPLRLFPDPLMQQFAAQGD---PSSM 426
                    .|:.:|.:.|..        |::| |.:..|:|.....:...:.|.|:.|   ....
Frog   265 TGKPVKEAKSKNSDQENDSQGPQPHNDSESILRLRELFRAPENSDGETDPEAFNAEHDFFNCKDS 329

  Fly   427 ALFEKARQHLQMFGGNSP 444
            .|.......:|..|.|||
Frog   330 RLSNPDTPRIQSDGLNSP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mid	NP_001260096.1	TBOX	185..384	CDD:238106	91/236 (39%)
mga	XP_012824488.2	T-box_MGA-like	76..261	CDD:410321	87/198 (44%)
		DUF4801	996..1038	CDD:406462
		PHA03247	<1575..1860	CDD:223021
		MSCRAMM_ClfB	<1952..2219	CDD:411414
		MDN1	<2090..2458	CDD:227596
		bHLH_SF	2475..2539	CDD:412148
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920