Protein Alignment H15 and tbr1

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001072587.1
• Gene: tbr1 / 780042
• XenbaseID: XB-GENE-942241
• Length: 677
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 180/647 - (27%)
• Similarity: 248/647 - (38%)
• Gaps: 183/647 - (28%)

  Fly    58 HHHPL-----NNHHNHNHNQHNISFATDFSIAAIMARGGNAPSSREPSERS--LSPASVERYS-- 113
            |.||:     |...:....:..:...|:.|.|...:...:||...:.|:.|  |...|..|:|
 Frog    35 HDHPIISSADNLERSSPLKKATVRGMTNQSEADSFSGAKDAPGDGQRSKLSPVLDGVSEIRHSFD 99

  Fly   114 GQDADDDVDVDVVDCSDSEMP--SATAAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQ 176
            |..||..:           :|  |.:.:||:|.||.                       ......
 Frog   100 GSAADRYL-----------LPQSSQSQSAASAPTTT-----------------------MFPYPS 130

  Fly   177 QRQQTHHHATTGKQQRQHHNHHSSNTNNSSNS--GNSNTNSKSSSQRGRSAAAVGAAATPSPPPP 239
            |....|...:.|...| :..||....|.:.||  |||                       :|...
 Frog   131 QHGAAHPAFSLGSPGR-YMAHHPVIANGAYNSLLGNS-----------------------APQGY 171

  Fly   240 PPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTP--VQCHLETKELWDKFHELGTEMIITKS 302
            |.:..|     .|.:...:.|..|....|.....|.|  .|.:|..:.||.|||...|||||||.
 Frog   172 PSAGYP-----YSQQYGHSYQAAPFYQFSATQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQ 231

  Fly   303 GRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADP-PPPSRIYA 366
            ||||||.:..:.||    :.|...|.:.:||:..|...:|  :....|:..||||. ...:|:|.
 Frog   232 GRRMFPFLSFNISG----LDPTAHYNIFVDVILADPNHWR--FQGGKWVPCGKADTNVQGNRVYM 290

  Fly   367 HPDCPLSPEALRKQVVSFEKVKLTNNE--MDKSGQ-VVLNSMHRYQPRIHLVRLSH-GQSIPGSP 427
            |||.|.:.....:|.:||.|:|||||:  .:.:|| |||.|:|:||||:|:|.::. |......|
 Frog   291 HPDSPNTGAHWMRQEISFGKMKLTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNEDGTEDTSQP 355

  Fly   428 KELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRL----SDFDRDPMDAFF 488
            ..:|     ||.||||.|.|||||||..||:||||.|||||||||:...    .|.||
 Frog   356 GRVQ-----TFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDTIYTGCDLDR------- 408

  Fly   489 FDQHMRTAPLRFFPDPLMSQLTPQEADAASMALLE--------KARQHLQMFGRSPYTEMLLPH- 544
                :..:|    .|...||:.|....:.:...|:        |:|.|.......|.|:..:||
 Frog   409 ----LTPSP----NDSPRSQIVPGARYSMASTFLQDQFVSNYAKSRFHPPGAVPGPGTDRSVPHT 465

  Fly   545 --LYQRSAAPPPPPPAPHLSAFQLGMWQQQWPQLTAGFLASANQQ-------------------- 587
              |........|..|:|           |:|      |:..||.:
 Frog   466 NGLLSPQQGEDPGAPSP-----------QRW------FVTPANNRLDFTSASAYDAATDFAGNAA 513

  Fly   588 AALALAAAGANRTPPPSMAVAPPAPATPTSSCGSASPDLRARPQLNHY--PQRFSPYQVPQH 647
            ..|:.||||....|            .|...|       .||| |.:|  |..:.....||:
 Frog   514 TLLSYAAAGVKALP------------LPGGGC-------TARP-LGYYSDPTGWGARSPPQY 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	92/200 (46%)
tbr1	NP_001072587.1	T-box_TBR1	205..395	CDD:410330	91/200 (46%)
		T-box_assoc	420..675	CDD:465042	35/173 (20%)