Protein Alignment H15 and TBX6

DIOPT Version :9

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_004599.2
• Gene: TBX6 / 6911
• HGNCID: 11605
• Length: 436
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 150/391 - (38%)
• Similarity: 185/391 - (47%)
• Gaps: 84/391 - (21%)

  Fly   222 GRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKEL 286
            |..||....||.|..|..||:...|          ||.. .|:.:.|     |..|...||.:||
Human    52 GMEAAPRTLAAHPPLPLLPPAMGTE----------PAPS-APEALHS-----LPGVSLSLENREL 100

  Fly   287 WDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWL 351
            |.:|..:||||||||:||||||..|||.:|    :.|..||..||||:|:|..|||:...|  |.
Human   101 WKEFSSVGTEMIITKAGRRMFPACRVSVTG----LDPEARYLFLLDVIPVDGARYRWQGRR--WE 159

  Fly   352 VAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVR 416
            .:|||:|..|.|:|.|||.|.:.....:|.|||.:|||||:.:|..|.::|:|||:|||||||||
Human   160 PSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVR 224

  Fly   417 LSH--GQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDF 479
            .:.  .|...|.         .:|.||||.|.:||||||..||:|||.:||||||||::.|....
Human   225 AAQLCSQHWGGM---------ASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKR 280

  Fly   480 DRD--------------------------PMDAFF------FDQHMRTAP--LRFFPDPLMSQLT 510
            :||                          |.|:..      .|.....||  ....|.||... .
Human   281 ERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGG-P 344

  Fly   511 PQEADAASMALLEKARQHLQM----------FGRS-PYTE--MLLPHLYQRS---AAPPPPPPAP 559
            ..||.....|....|..||..          .||| ||:.  :.|||....|   ||||..|.||
Human   345 SAEAYLLHPAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAP 409

  Fly   560 H 560
            |
Human   410 H 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	TBOX	276..475	CDD:238106	101/200 (51%)
TBX6	NP_004599.2	TBOX	90..277	CDD:238106	101/201 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..339		11/67 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..379		3/18 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740