DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H15 and mgaa

DIOPT Version :9

Sequence 1:	NP_608926.2	Gene:	H15 / 33769	FlyBaseID:	FBgn0016660	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	XP_005158676.1	Gene:	mgaa / 569620	ZFINID:	ZDB-GENE-030603-1	Length:	2838	Species:	Danio rerio

Alignment Length:	279	Identity:	101/279 - (36%)
Similarity:	146/279 - (52%)	Gaps:	42/279 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 SSNSGNSNTNSKSSSQ---RGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEES-PAQQPTPKI 265
            ||:|||...|..:.|:   .|:|:.....|..     .|.|.:..:....:|.|: ||
Zfish    41 SSDSGNDKANLMAISEANKMGKSSIGTTVAGI-----QPTSSTFADTNSTTPSENLPA------- 93

  Fly   266 VGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVL 330
              ...|..:|..   |:...:|::||...||||:||.||||||..|...||    ::|...|.:.
Zfish    94 --DARCRGITVT---LDNNNMWNEFHRCKTEMILTKQGRRMFPYCRFRLSG----MEPFQNYVLA 149

  Fly   331 LDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMD 395
            :|:.|.|:.||:::  ...|...|||: |..||::.||:.|.|.....:..|||.::||.|. :|
Zfish   150 MDIKPADNCRYKWS--GKGWEPNGKAE-PHISRLFVHPESPASGLHWMQYPVSFYRLKLCNT-LD 210

  Fly   396 KSGQVVLNSMHRYQPRIHLVRLSHGQSIPGS--PKELQDMDHK---TFVFPETVFTAVTAYQNQL 455
            :.|.::|:|||||.|:||:        ||..  .|::..:|..   |..|.:|.|.|||||||..
Zfish   211 QEGHIILHSMHRYLPQIHI--------IPADKVSKDILILDRPNVVTLSFAQTEFFAVTAYQNLC 267

  Fly   456 ITKLKIDSNPFAKGFRDSS 474
            ||:||||.||||||||:.:
Zfish   268 ITQLKIDYNPFAKGFREDA 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	TBOX	276..475	CDD:238106	83/204 (41%)
mgaa	XP_005158676.1	T-box	102..284	CDD:279278	82/200 (41%)
		DUF4801	1321..1366	CDD:292677
		NTR2	<2131..2271	CDD:292097
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740