Protein Alignment H15 and tbx3a

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001095140.2
• Gene: tbx3a / 556870
• ZFINID: ZDB-GENE-070209-80
• Length: 689
• Species: Danio rerio
• Alignment Length: 611
• Identity: 179/611 - (29%)
• Similarity: 237/611 - (38%)
• Gaps: 221/611 - (36%)

  Fly   218 SSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTPVQCHLE 282
            :::.|...:::|..|....|          |:.|.|||.....|                :.|||
Zfish    65 AAETGLHFSSLGHQAAHLRP----------LKTLEPEEEVEDDP----------------KVHLE 103

  Fly   283 TKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHR 347
            .||||:.||:.||||:||||||||||..:|..:|    :....:|.:|:|:|..|..||:  :|.
Zfish   104 AKELWELFHKRGTEMVITKSGRRMFPPFKVRCTG----LDKKAKYILLMDIVAADDCRYK--FHN 162

  Fly   348 SSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRI 412
            |.|:|||||||..|.|:|.|||.|.:.|....:||:|.|:|||||..||.|..:|||||:||||.
Zfish   163 SRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVNFHKLKLTNNISDKHGFTILNSMHKYQPRF 227

  Fly   413 HLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDS---- 473
            |:||.:....:|.|       ..:|:|||||.|.|||||||..||:||||.|||||||||:
Zfish   228 HIVRANDILKLPYS-------TFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGR 285

  Fly   474 ----------------------------------------------------SRLSDFDRDPMDA 486
                                                                :.|.||.....|:
Zfish   286 REKRKQLALQSMRSYEEQQKKENGTSDDSSGEQASFKCFRQASSPAVSTAGHNHLKDFCDSDEDS 350

  Fly   487 FFFDQHMRTAPLRFFPDPLMSQLTPQ---------------EADAASMALLEKARQHLQMFGRSP 536
               |:..:.|..:..||......|.:               |:|::|....||.|..    .|||
Zfish   351 ---DEEDKDANAKEGPDSSKISTTTEDSKDQDAGLGKSVFGESDSSSGRRSEKTRAD----SRSP 408

  Fly   537 YT-------------------------------EMLLPHLYQRSAAPPPPPPAPHLSAFQLGMWQ 570
            .|                               |..:|...|...|........|...|..|:..
Zfish   409 ITLISSTTRSGEELKSPVREPAKTTDDCRTVSKENYMPLTVQTDGAAHLNQNHLHNFGFPPGLAG 473

  Fly   571 QQWPQLTAG---FL---ASANQQAALALAAAG-----------------ANRTPPPS-------- 604
            ||:.....|   ||   :..|...|.:..|||                 .:..|.||
Zfish   474 QQFFNHLGGAHPFLLHPSQFNMGGAFSNMAAGMGPILAAVSSGGVGSLDGSSLPSPSQSLTGAPM 538

  Fly   605 -------------MAVAP-----PAP------ATPTSSCGSAS----PDLRA-RPQLNHYPQRFS 640
                         :|::|     |.|      |...||..|:|    |.|.| ||:|     |:|
Zfish   539 PFHLQQHVLASQGLAMSPFGGLFPYPYTYMAAAAAASSAASSSVHRHPFLSAVRPRL-----RYS 598

  Fly   641 PYQVPQHQAS--------PPASNRAE 658
            ||.:|....|        |.||:..|
Zfish   599 PYSLPSVPDSTLLTTAMQPMASSGLE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	104/195 (53%)
tbx3a	NP_001095140.2	T-box_TBX2_3-like	99..280	CDD:410314	103/193 (53%)
		TBX	298..379	CDD:432659	9/83 (11%)