Protein Alignment H15 and TBX22

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_058650.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 167/474 - (35%)
• Similarity: 216/474 - (45%)
• Gaps: 116/474 - (24%)

  Fly   219 SQRGRS---AAAVGAAATPSPPPPPPSQSP---------EELERLSP--------EESPAQQPTP 263
            |.|.|:   .|.||..:......|..::.|         ||.||.|.        |:.|..:|:.
Human     4 SSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPST 68

  Fly   264 KIVGSCNCD----------DLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPL 318
            .....|..|          :...:|..|:..|||.:||::||||||||:||||||:|||...|
Human    69 SASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKG-- 131

  Fly   319 RQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKAD-----PPPPSRIYAHPDCPLSPEALR 378
              :.|..:|.|.:||||:||:||||.||.|.|:|||..|     |    |.|.|||.|.|.|...
Human   132 --LDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIP----RFYVHPDSPCSGETWM 190

  Fly   379 KQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVR------LSHGQSIPGSPKELQDMDHKT 437
            :|::||:::||||||||..|.::|.|||:|:||:|::.      ||..||:|..       ..||
Human   191 RQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTE-------GVKT 248

  Fly   438 FVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAPLR--F 500
            |.|.||.||.|||||||.||||||:.|||||||||:.|    :|..:|..     :.|.|.|  |
Human   249 FSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGR----NRGVLDGL-----LETYPWRPSF 304

  Fly   501 FPDPLMSQLTPQEADAASMALLEKARQHLQMFGRSPYTEMLLPHLYQRSAAPPPPPPAPHLSAFQ 565
            ..|........|...:.|..:.....      ..||...:|.|..:.         |..||....
Human   305 TLDFKTFGADTQSGSSGSSPVTSSGG------APSPLNSLLSPLCFS---------PMFHLPTSS 354

  Fly   566 LGM-----------------------WQQQWPQLTA-GFLASANQQAALALAAAGANRTPPPSMA 606
            |||                       ||||...|.| ..|||:|...:||          |..|.
Human   355 LGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLA----------PLMME 409

  Fly   607 VAPPAPATPTSSCGSASPD 625
            |...:....|:|...:|.|
Human   410 VPMLSSLGVTNSKSGSSED 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	109/206 (53%)
TBX22	NP_058650.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91		18/86 (21%)
		T-box_TBX22-like	90..283	CDD:410326	108/207 (52%)