Protein Alignment H15 and tbx6

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001007995.1
• Gene: tbx6 / 493357
• XenbaseID: XB-GENE-6257419
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 156/491 - (31%)
• Similarity: 211/491 - (42%)
• Gaps: 144/491 - (29%)

  Fly   233 TPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEM 297
            ||...||.|:....:|      :.|.:  ||::.|:        |:.:||.||||.:||.:||||
 Frog    68 TPLSLPPGPALGFGQL------QPPCE--TPQLPGN--------VKMNLENKELWKQFHSIGTEM 116

  Fly   298 IITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPS 362
            |||||||||||..:||.:|    ::|..:|.:|.|:||:|:.||::...|  |..:|:|:|..|.
 Frog   117 IITKSGRRMFPQCKVSVTG----LEPDGKYLLLADIVPIDNSRYKWQEDR--WEPSGRAEPRLPE 175

  Fly   363 RIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGSP 427
            |:|.|||.|.......||.:||.|:|||||.:|:.|.::|:|||:||||.|:||
 Frog   176 RVYIHPDSPAPGSHWMKQPISFHKIKLTNNTLDQMGHIILHSMHKYQPRFHIVR----------- 229

  Fly   428 KELQDMDHK------TFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRD---- 482
              .||:..:      :|.||||:|..||||||:.||:|||.:||||||||:....|..||.
 Frog   230 --AQDVFSRRWGGCSSFTFPETLFLTVTAYQNEKITQLKIQTNPFAKGFREDGMKSKRDRSTRVK 292

  Fly   483 --------------------------PMDAFFFDQ------------------HMRTAPLRFFPD 503
                                      |.|:...::                  |..|.|.|..|.
 Frog   293 RKVIEPEEEEEEFQPEGECKRPLYTGPCDSTLSEELDIGRGLGIPLPSPDCSFHPITPPSRTPPS 357

  Fly   504 ---PLMSQLTPQEADAASMALLEKARQHLQMFGRSPYTEMLLPHLYQRSAAPP-------PPPPA 558
               |..|....||..||.....:.....||..|:| |.|.           ||       |.|..
 Frog   358 TQTPNPSLTANQEQGAALEMSSQTPETFLQAAGQS-YPEQ-----------PPVRGGSLYPCPTD 410

  Fly   559 PHLSAFQ---LGMWQQQWPQLTAGFLASANQQAALALAAAG----ANRTPPPSMAVAPPAPATPT 616
            .|.:..|   |.:  |:.||...|...|............|    .....|||.||||
 Frog   411 GHGAQNQRHPLSV--QRLPQAFQGLQESLGNSPGEYKIYGGDVGCGGDFAPPSCAVAP------- 466

  Fly   617 SSCGSASPDLRARPQLNHYPQRFS-------PYQVP 645
                      ..||.....|:.:|       |:.:|
 Frog   467 ----------SVRPSEERLPRGYSMNSELRFPHFLP 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	98/201 (49%)
tbx6	NP_001007995.1	T-box_TBX6	96..278	CDD:410322	97/200 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..318		5/41 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..418		22/96 (23%)