Protein Alignment H15 and bi

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 805
• Identity: 216/805 - (26%)
• Similarity: 299/805 - (37%)
• Gaps: 303/805 - (37%)

  Fly     8 ANTKPQQTPSPSQTQNFKSKLQQQIVSAAAAAAANIANGSSHHHHHQNHHHHHPLNNHHNHNHNQ 72
            |...||...|.|.|                ...:|..|.||:::::.:.|:::  |||.|:|:|.
  Fly    91 AQLSPQSNHSSSNT----------------TTTSNTNNSSSNNNNNNSTHNNN--NNHTNNNNNN 137

  Fly    73 HNISFATDFSIAAIMARGGNAPSSREPSERSLSPASVERYSGQDADDDVDVDVVDCSDSEMPSAT 137
            :|         .....:|.:..::.||...:.:|...               :|.......|:..
  Fly   138 NN---------NTSQKQGHHLSTTEEPPSPAGTPPPT---------------IVGLPPIPPPNNN 178

  Fly   138 AAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQQRQQTHHHATTGKQQRQHHNHHSSNT 202
            ::::::..:|:|||                            ...||.|..        |||.:|
  Fly   179 SSSSSSNNSASAAA----------------------------HPSHHPTAA--------HHSPST 207

  Fly   203 NNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSP-----------------PPPPPSQSPEELER 250
                               |.:|...||...|.|                 |||||......|..
  Fly   208 -------------------GAAAPPAGATGLPPPTPPHHLQQQQQQQQHPAPPPPPYFPAAALAA 253

  Fly   251 LS------------------PEESPAQQPTPKIVGSC--NCDDLTPV-----QCH---------- 280
            |:                  |...|...|....:||.  ..:|:...     |.|
  Fly   254 LAGSPAGPHPGLYPGGGLRFPPHHPGAHPHAHHLGSAYTTAEDVVLASAVAHQLHPAMRPLRALQ 318

  Fly   281 -------------LETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLD 332
                         ||.|:||:|||:|||||:||||||:|||.::...||    :....:|.:|||
  Fly   319 PEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSG----LDAKAKYILLLD 379

  Fly   333 VVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKS 397
            :|..|.  |||.:|.|.|:|||||||..|.|:|.|||.|.:.|...::||||.|:|||||..||.
  Fly   380 IVAADD--YRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKH 442

  Fly   398 GQV---VLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKL 459
            |.|   :|||||:||||.||||.:....:|.|       ..:|:||.||.|.|||||||:.||:|
  Fly   443 GFVSTTILNSMHKYQPRFHLVRANDILKLPYS-------TFRTYVFKETEFIAVTAYQNEKITQL 500

  Fly   460 KIDSNPFAKGFRD-------------SSRLSDFDRDPMDAFFFDQHMRTAPLRFFPDPLMSQLTP 511
            |||:|||||||||             |:|.||.|:                           |.|
  Fly   501 KIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDK---------------------------LNP 538

  Fly   512 QEADAASMALLEKARQHLQMFGRSPYTEMLLPHLYQRSA----------------APPPPPPAPH 560
            ....::      :|..||...||.       |||:..:|                .||..|..|.
  Fly   539 THVSSS------RAPLHLGHAGRP-------PHLHPHAALLDNQQDDDDKLLDVVGPPQSPLLPL 590

  Fly   561 LSAFQLGMWQQQWPQLTAGF--LASANQQAALALAAAGANRTPPPSM------------------ 605
            ..:.|.....|....|.|.|  ||.|...|:...|||.||.:...::
  Fly   591 SHSLQQMHAHQHSAALAAWFNHLAGAGAGASEHAAAAAANASAEDALRRRLQADADVERDGSDSS 655

  Fly   606 -----------AVAPPAPATPTSSCGSA----------------SPDLRARPQLNHYPQRFSPYQ 643
                       |..|.:..:|..:.|:|                ||::...|.::..| ...||.
  Fly   656 CSESVGGSTGGAFRPTSTGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSP-HLLPYL 719

  Fly   644 VPQHQASP--------PASNRAESP 660
            .|.....|        ||:..|.||
  Fly   720 YPHGLYPPPHLGLLHNPAAAAAMSP 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	110/239 (46%)
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:337907	8/57 (14%)
		T-box_TBX2_3-like	326..513	CDD:410314	106/199 (53%)