Protein Alignment H15 and Tbx5

DIOPT Version :9

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001009964.1
• Gene: Tbx5 / 304514
• RGDID: 1305702
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 495
• Identity: 154/495 - (31%)
• Similarity: 221/495 - (44%)
• Gaps: 135/495 - (27%)

  Fly   214 NSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTPVQ 278
            :||..|...:..:|:||          ||:||.     ||:.:..||            .:..::
  Rat    18 DSKDRSCDSKPESALGA----------PSKSPS-----SPQAAFTQQ------------GMEGIK 55

  Fly   279 CHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRY 343
            ..|..:|||.||||:||||||||:||:|||:.:|..:|    :.|..:|.:|:|:||.|..||::
  Rat    56 VFLHERELWLKFHEVGTEMIITKAGRQMFPSYKVKVTG----LNPKTKYILLMDIVPADDHRYKF 116

  Fly   344 AYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRY 408
            |.::  |.|.|||:|..|.|:|.|||.|.:.....:|:|||:|:|||||.:|..|.::|||||:|
  Rat   117 ADNK--WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKY 179

  Fly   409 QPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDS 473
            |||:|:|:....... ||    ::....|.|||||.|.|||:|||..||:|||::||||||||.|
  Rat   180 QPRLHIVKADENNGF-GS----KNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGS 239

  Fly   474 SRLSDFDRDPMDAFFFDQHMRTAPLRFFPDPLMSQLTPQEADAASMALLEKARQHLQMFGRSPY- 537
            ..|             :.| |.:.:|....|::.:.|          :..|...|      ||:
  Rat   240 DDL-------------ELH-RMSRMRSKEYPVVPRST----------VRHKVANH------SPFS 274

  Fly   538 -------TEMLLPHLYQ---------RSAAPPPPP------------------------------ 556
                   |...|...||         :...|||.|
  Rat   275 SETRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLAQEHSQIYHCTKRKDEECSSTEHPYKK 339

  Fly   557 ------PAPHLSAFQLGMWQQQWPQLTAGFLASANQQAALALAAAGANRTPPPSMAVAPPAPATP 615
                  |:...:.::.|..|||      |...|...::|...|...|:..||     :.|.|:..
  Rat   340 PYMETSPSEEDTFYRSGYPQQQ------GLSTSYRTESAQRQACMYASSAPP-----SEPVPSLE 393

  Fly   616 TSSCGS--ASPDLRARPQLNHYPQRFSPYQ-VPQHQASPP 652
            ..||.:  :.|...:.......|....||| ...|..|.|
  Rat   394 DISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGP 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	TBOX	276..475	CDD:238106	98/198 (49%)
Tbx5	NP_001009964.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46		12/42 (29%)
		TBOX	53..241	CDD:238106	98/198 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..313		11/48 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..369		7/43 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740