Protein Alignment H15 and Tbx4

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_006247098.1
• Gene: Tbx4 / 303399
• RGDID: 1309057
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 164/524 - (31%)
• Similarity: 238/524 - (45%)
• Gaps: 139/524 - (26%)

  Fly   205 SSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKI-VGS 268
            :|||.|:|....:.:..|.|..|:.:         ||.|..:.....:...:.|:|....| ||
  Rat    24 TSNSNNTNVPEPALATPGLSGTALSS---------PPGQGADVAAAAAAAAAAAEQTIENIKVG- 78

  Fly   269 CNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDV 333
                        |..||||.||||.||||||||:||||||:.:|..:|    :.|..:|.:|:|:
  Rat    79 ------------LHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTG----MNPKTKYILLIDI 127

  Fly   334 VPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSG 398
            ||.|..||::..::  |:|||||:|..|.|:|.|||.|.:.....:|:|||:|:|||||.:|..|
  Rat   128 VPADDHRYKFCDNK--WMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG 190

  Fly   399 QVVLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDS 463
            .::|||||:||||:|:|:.....:. ||    ::....|.|||||.|.:||:|||..||:|||::
  Rat   191 HIILNSMHKYQPRLHIVKADENNAF-GS----KNTAFCTHVFPETSFISVTSYQNHKITQLKIEN 250

  Fly   464 NPFAKGFRD-----------------------------SSRLS-DFDRDPMDA-------FFFDQ 491
            ||||||||.                             ||:|| ..|..|:.:       :.::.
  Rat   251 NPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLVSSQLSAKPDVSPLHSTHQALQHYQYEN 315

  Fly   492 --HMRTA-------PLRFFPDPLMSQL----TPQEADAASMALLEKARQHLQMFGRSPYTEMLLP 543
              ||:.|       ||..||....|.|    ..:.||:|         :||.:..:..|.|  .|
  Rat   316 GAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRRADSA---------RHLDLPCKRSYLE--TP 369

  Fly   544 ------HLYQRSAAPPPPPPAPHLSAFQLGMWQQQWPQLTAGFLASANQQAALALAAAGANRTPP 602
                  |.::   :|||              :.||  .|:..:.:....:.|...:::|......
  Rat   370 SSVGDDHYFR---SPPP--------------YDQQ--MLSPSYCSEVTPREACMYSSSGPEIAGV 415

  Fly   603 PSMAVAPPAPATPTSSCG---SASPDLRARPQLNHYPQRFSPYQ-VPQHQAS-------PPASNR 656
            .::...||.|.    ||.   |.||......|    .....||| .|.|..:       |.|:..
  Rat   416 SAVDDLPPPPL----SCNMWTSVSPYTSYSVQ----TMETVPYQPFPTHFTATTMMPRLPIAAQS 472

  Fly   657 AESP 660
            |:.|
  Rat   473 AQPP 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	98/224 (44%)
Tbx4	XP_006247098.1	T-box_TBX4_5-like	75..259	CDD:410315	100/207 (48%)