Protein Alignment H15 and Tbx22

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001421332.1
• Gene: Tbx22 / 302369
• RGDID: 1589764
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 183/618 - (29%)
• Similarity: 251/618 - (40%)
• Gaps: 199/618 - (32%)

  Fly   130 DSEMPSATAAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQQRQQTHHHATTGKQQRQH 194
            |:::|.|.::....|.::.|.|.:::| ...|.:.|.||..:::.|.:.|: ......|::..
  Rat     2 DTKIPPAASSLPGMALSSRAHAFSVEA-LMGRPSKRKAQDPREEMQPELQE-EQFIEEGEEIL-- 62

  Fly   195 HNHHSSNTNNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQ 259
                      ||.||:|.                                       .|.|...:
  Rat    63 ----------SSPSGDSE---------------------------------------QPAEKRPK 78

  Fly   260 QPTPKIVGSCNCDDLTP---------VQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFS 315
            ..:.|.|.||:.::...         :|..|:..:||.:||::||||||||:||||||:||:...
  Rat    79 AESSKTVFSCSDNESNSLESLLEESIIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVK 143

  Fly   316 GPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKAD----PPPPSRIYAHPDCPLSPEA 376
            |    :.|..:|.|:|||||:||:||||.||.|.|:|||..|    .|   |.|.|||.|.|.|.
  Rat   144 G----MDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITP---RFYVHPDSPCSGEN 201

  Fly   377 LRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVR------LSHGQSIPGSPKELQDMDH 435
            ..:|::||::|||||||||..|.::|.|||:|:||:|:|.      ||..||.|..       ..
  Rat   202 WMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVVEEDSRIDLSLIQSFPTE-------GV 259

  Fly   436 KTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAPLR- 499
            |||.|.||.||.|||||||.|||||||.|||||||||..|    :|..:|.|     :.|.|.|
  Rat   260 KTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGR----NRGVLDGF-----LETYPWRP 315

  Fly   500 --------FFPD-------------------PLMSQLTPQ--------EADAASMALLEKARQHL 529
                    |.||                   ||.|.|:|.        ...:..|...|....::
  Rat   316 SFTMDFKPFVPDTQNGSSGSSPVTSSGGAPSPLNSLLSPSCSPPTVYIPPSSIGMTHPETYLHNV 380

  Fly   530 QMFGRSPYTEMLLPHLYQRSAAPPPP---PPAPHLSAFQLGMWQQQWPQL--------TAGFLAS 583
            .:    |:...:.|..|.|    |.|   |....|.:|..   .|.:|.|        :.||:.|
  Rat   381 NV----PFCYRICPTNYWR----PQPFVLPTPERLPSFNS---SQSFPPLMMEVPLVSSRGFINS 434

  Fly   584 -----------------ANQQAALALAAAGANRTPPPSMAVAPPAPATPTSSC------------ 619
                             :..|....|...|....|.|....|...|..|.:.|
  Rat   435 NSGLHEDCNGHCLQASHSTSQMLYGLQNPGNIFHPNPIAQEAICCPFHPPNGCYRYNVSMPPRLE 499

  Fly   620 -----------------GSASPDLRARPQLNHY 635
                             |.:.......|.:|||
  Rat   500 NVANHLSENGTNQISFTGGSCDHSHWYPAINHY 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	111/205 (54%)
Tbx22	NP_001421332.1	T-box_TBX22-like	105..296	CDD:410326	110/204 (54%)