DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H15 and Mga

DIOPT Version :9

Sequence 1:	NP_608926.2	Gene:	H15 / 33769	FlyBaseID:	FBgn0016660	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	XP_006499750.1	Gene:	Mga / 29808	MGIID:	1352483	Length:	3091	Species:	Mus musculus

Alignment Length:	237	Identity:	97/237 - (40%)
Similarity:	134/237 - (56%)	Gaps:	22/237 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 LSPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFS 315
            ||.|.||.:. ..||....:| .:..:...|:...:|::||...||||:||.||||||..|...:
Mouse    51 LSRESSPGKS-KEKICLPADC-TVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWIT 113

  Fly   316 GPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQ 380
            |    :....:|.:::|:.|:||.||:  ::...|..:|||:|....|::.||:.|.:......|
Mouse   114 G----LDSNLKYILVMDISPVDSHRYK--WNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQ 172

  Fly   381 VVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSI-----PGSPKELQDMDHKTFVF 440
            .|||.|:|||||.:|:.|.::|:|||||.||:|||.......:     ||.         .||.|
Mouse   173 PVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKATEVIQLNGPGV---------HTFTF 228

  Fly   441 PETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRD 482
            |:|.|.|||||||..||:||||.|||||||||....|...|:
Mouse   229 PQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLSSKPQRE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	TBOX	276..475	CDD:238106	87/203 (43%)
Mga	XP_006499750.1	TBOX	74..264	CDD:238106	87/204 (43%)
		DUF4801	1038..1080	CDD:374336
		DUF5585	<1510..>1811	CDD:375359
		Atrophin-1	1729..>2023	CDD:367360
		bHLHzip_MGA	2452..2516	CDD:381481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750