DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment H15 and Tbx15

DIOPT Version :9

Sequence 1:	NP_608926.2	Gene:	H15 / 33769	FlyBaseID:	FBgn0016660	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_001382004.1	Gene:	Tbx15 / 295315	RGDID:	1308094	Length:	602	Species:	Rattus norvegicus

Alignment Length:	506	Identity:	169/506 - (33%)
Similarity:	236/506 - (46%)	Gaps:	99/506 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 THHHATTGKQQRQHHNHHSSNTNNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSP 245
            |...||.|.:.   |.....:|.:.|......|:...|:....::.|.|:.       |....|.
  Rat    56 TDDPATHGLEP---HPDSEQSTGSDSEVLTERTSCSFSAHTDLASGAAGSV-------PVAMSSM 110

  Fly   246 EELERLSPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTV 310
            ||                             :|..|:..:||.:||::||||||||:||||||.:
  Rat   111 EE-----------------------------IQVELQCADLWKRFHDIGTEMIITKAGRRMFPAM 146

  Fly   311 RVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPE 375
            ||..:|    :.|..:|.:.:|:||:|::||||.||.|.|:|||.||.|.|.|:|.|||...|.:
  Rat   147 RVKITG----LDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGD 207

  Fly   376 ALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSI-PGSPKELQDMDHKTFV 439
            ...:|||||:|:||||||:|..|.::|:|||:||||:|::|......: |..|..:.| ..|||.
  Rat   208 TWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGD-GVKTFN 271

  Fly   440 FPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAF-----FFDQHMRTAPLR 499
            |||||||.|||||||.||:||||.||||||||||.|    :|..::|.     |:...:||....
  Rat   272 FPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGR----NRTGLEAIMETYAFWRPPVRTLTFE 332

  Fly   500 FFPDPLMSQLTPQEADAASMALLEKARQHLQMFGRSPYTE-------MLLPHLYQRSAAPPPPPP 557
            .|       .|.|:....|.             |.||.|.       ....||...|.:||....
  Rat   333 DF-------TTMQKQQGGST-------------GTSPSTSSTGTPSPSASSHLLSPSCSPPTFHL 377

  Fly   558 APHLSAFQLGMWQQQ--------WPQLTAGFLASANQQAALALAAAGANRTPPPSMAVAPPAPA- 613
            ||  :.|.:|..:.|        :|......:|:.  |:...|:.:|.||....:.:...|:..
  Rat   378 AP--NTFNVGCRESQLCNLNLSDYPPCARSNMAAL--QSYPGLSDSGYNRLQSGTASATQPSETF 438

  Fly   614 ----TPTSSCG-SASPDLRARPQLNHYPQRFSPYQVPQHQASPPASNRAES 659
                ||:...| ...|.|.:..::..|..:...:...|.|....|.|.|.|
  Rat   439 MPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	TBOX	276..475	CDD:238106	110/199 (55%)
Tbx15	NP_001382004.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3147
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.790