Protein Alignment H15 and Tbx22

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_851836.2
• Gene: Tbx22 / 245572
• MGIID: 2389465
• Length: 531
• Species: Mus musculus
• Alignment Length: 561
• Identity: 174/561 - (31%)
• Similarity: 237/561 - (42%)
• Gaps: 184/561 - (32%)

  Fly   130 DSEMPSATAAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQQRQQTHHHATTGKQQRQH 194
            |:|:|:|.::....|.::.|.|.:::| ...|.:.|.||..:::.|.:.|:
Mouse     2 DTEIPTAASSLPGMALSSRAHAFSVEA-LMGRPSKRKAQDPREEMQPELQE-------------- 51

  Fly   195 HNHHSSNTNNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQ 259
                    ......|.....|                      |...||.||  :||..|.|
Mouse    52 --------EQFVEEGEEILRS----------------------PSRDSQQPE--KRLKAESS--- 81

  Fly   260 QPTPKIVGSC--------NCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSG 316
                |.|.||        :..:.:.:|..|:..:||.:||::||||||||:||||||:||:...|
Mouse    82 ----KTVFSCSDESNSQESLQEESVIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKG 142

  Fly   317 PLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKAD----PPPPSRIYAHPDCPLSPEAL 377
                :.|..:|.|:|||||:||:||||.||.|.|:|||..|    .|   |.|.|||.|.|.|..
Mouse   143 ----MDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITP---RFYVHPDSPCSGENW 200

  Fly   378 RKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVR------LSHGQSIPGSPKELQDMDHK 436
            .:|::||::|||||||||..|.::|.|||:|.||:|:|.      ||..:|.|..       ..|
Mouse   201 MRQIISFDRVKLTNNEMDDKGHIILQSMHKYNPRVHVVEQDSRIDLSLIESFPTE-------GVK 258

  Fly   437 TFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAP-LRF 500
            ||.|.||.||.|||||||.|||||||.|||||||||..|    :|..:|.|     :.|.| :..
Mouse   259 TFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGR----NRGVLDGF-----LETYPWMPS 314

  Fly   501 FPDPLMSQLTPQEADAASMALLEKARQHLQMFGRSPYTEMLLPHLYQRSAAPPPPPPAPHLSAFQ 565
            |.....:.:|..::.::               |.||.|.         |...|.|
Mouse   315 FSMDFKTFVTDTQSGSS---------------GSSPVTS---------SGGAPSP---------- 345

  Fly   566 LGMWQQQWPQLTAGFLASANQQAALALAAAGANRTPPPSMAVAPPAPATPTSSCGSASPDL---- 626
                                           .|....||  .:||....|.||.|...||.
Mouse   346 -------------------------------LNSLLSPS--CSPPMVYIPPSSFGMTYPDAYLHS 377

  Fly   627 ---------------RARPQLNHYPQRFSPYQVPQHQASPP 652
                           |::|.:...|:|...:.:|  |..||
Mouse   378 VNIPFCYRICPTNNWRSQPFVLPTPERLPSFIIP--QTLPP 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	110/205 (54%)
Tbx22	NP_851836.2	T-box	103..294	CDD:469628	109/204 (53%)